Background: The current guidelines recommend patient stratification based on transthoracic echocardiography (TTE) to identify individuals with potential pulmonary hypertension (PH). We validated the relationship between PH and the pulmonary artery diameter (PAD) on computed tomography (CT) with peak tricuspid regurgitant velocity (TRV) measured by TTE for referral of patients with suspected PH for TTE screening.

Methods: We performed a retrospective analysis of CT-based PAD of 2356 patients who underwent TTE from February 2, 2013 to December 25, 2019 at our institution. The thresholds for suspected PH based on TRV were determined using receiver operating characteristic curves based on PAD. Pearson's rank correlation coefficient was used to assess the relationship between PAD and TRV.

Results: The area under the curve (AUC) of the PAD for suspected PH was statistically greater or comparable to others. The sex-specific PAD threshold for high PH probability were 29.4 mm (male: AUC, 0.86; sensitivity, 84.9%; specificity, 72.3%) and 27.8 mm (female: AUC, 0.83; sensitivity, 78%; specificity, 75.6%). Pearson's rank correlation coefficient showed a correlation between the PAD and TRV (male: ρ = 0.40, P < 0.001, female: ρ = 0.43, P < 0.001).

Conclusions: The main PAD on CT findings served as a suitable marker for referral of patients with suspected PH for TTE screening. Patients exceeding the CT-derived PAD threshold, even incidentally, should undergo additional TTE for a comprehensive PH assessment.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12574-024-00674-8DOI Listing

Publication Analysis

Top Keywords

pulmonary artery
12
artery diameter
8
transthoracic echocardiography
8
pulmonary hypertension
8
pearson's rank
8
rank correlation
8
correlation coefficient
8
pad
7
determining pulmonary
4
diameter scans
4

Similar Publications

Background: High levels of catecholamines are cardiotoxic and associated with stress-induced cardiomyopathies. Septic patients are routinely exposed to endogenously released and exogenously administered catecholamines, which may alter cardiac function and perfusion causing ischemia. Early during human septic shock, left ventricular ejection fraction (LVEF) decreases but normalizes in survivors over 7-10 days.

View Article and Find Full Text PDF

Subclavian artery pseudoaneurysms (SAPs) are rare and most often secondary to trauma. On the contrary, a mycotic origin is exceedingly rare, and defining this etiology can become challenging. We present a rare case of a tuberculous SAP in a young patient.

View Article and Find Full Text PDF

Background: Right ventricular restrictive physiology (RVRP) is a common occurrence in repaired tetralogy of Fallot (rTOF). The relationship of RVRP with biventricular blood flow components and kinetic energy (KE) from 4-dimensional (4D) flow cardiovascular magnetic resonance (CMR) is unclear.

Objectives: The purpose of this study was to investigate the association of 4D flow CMR parameters with RVRP in rTOF patients.

View Article and Find Full Text PDF

Background: Alcohol dependence remains a significant global health issue, exacerbated by the coronavirus disease 2019 (COVID-19) pandemic. Phosphatidylethanol (PEth), a direct biomarker of recent alcohol consumption, offers improved specificity, sensitivity, and a longer detection window of 2 - 4 weeks compared to traditional biomarkers. This study evaluates the association between PEth testing and hospital outcomes in hospitalized patients by comparing outcomes among patients with positive PEth and negative PEth test results.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!