A rare case of a pure yolk sac testicular tumour presenting in an adult with learning difficulties is presented. Pure yolk sac tumours are much more common in children, but when they do occur in adults, onset can be both insidious and aggressive. The best practice for identification involves the precise use of ultrasound, blood tests for tumour markers and FDG-PET/CT imaging for staging. Dual-phase treatment in the form of radical inguinal orchidectomy performed expediently followed by chemotherapy is the mainstay of treatment in advanced cases.
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| http://dx.doi.org/10.7759/cureus.74332 | DOI Listing |
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Pure Yolk Sac Testicular Tumour in an Adult: A Diagnostic Dilemma.
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November 2024
Andrology, University College London, London, GBR.
A rare case of a pure yolk sac testicular tumour presenting in an adult with learning difficulties is presented. Pure yolk sac tumours are much more common in children, but when they do occur in adults, onset can be both insidious and aggressive. The best practice for identification involves the precise use of ultrasound, blood tests for tumour markers and FDG-PET/CT imaging for staging.
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View Article and Find Full Text PDFArticle Synopsis
- The study investigates the occurrence of rete hyperplasia and hyaline globules in germ cell tumors, with a focus on their potential to mimic yolk sac tumors, noting a significant misdiagnosis risk over the years.
- Out of 348 evaluated orchiectomies, 30% showed rete hyperplasia and/or hyaline globules, often without any yolk sac tumor component, suggesting a complexity in tumor classifications.
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