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Objective: To analyze the status and epidemic trends of major chronic metabolic diseases among adults.
Methods: Using the "China Health and Nutrition Survey"(2009-2018)/"China Development and Nutrition Health Impact Cohort Survey"(2022-2023), adults aged 18 years old and above from 10 provincial regions were selected as the study subjects. Those with missing demographic information and disease diagnosis were removed, and a total of 34 982 people were finally included from 2009, 2015, 2018 and 2023 waves. The prevalence trend of hypertension, diabetes, dyslipidemia and hyperuricemia, as well as the differences in age, gender, urban/rural and regions were described and analyzed. Multiple logistics regression models were fitted to analyze the relations of various chronic metabolic diseases.
Results: The prevalence of hypertension, diabetes, dyslipidemia and hyperuricemia among adults in 10 provincial regions increased from 31.71%, 10.86%, 34.96% and 11.39% in 2009 to 43.43%, 16.81%, 39.02% and 14.54% in 2023, respectively. Except for hyperuricemia, the prevalence of other chronic metabolic diseases increased with age. The prevalence of chronic metabolic diseases in males was significantly higher than that in females(P<0.01). Except for hypertension, the incidence of chronic metabolic diseases among urban residents was generally higher than that in rural areas(P<0.01), but the urban-rural difference was gradually decreasing. Regional differences showed different characteristics in each diseases. The prevalence of hypertension and diabetes in the north was higher than that in the south(P<0.01), however, the prevalence of hyperuricemia in the south was higher than that in the north(P<0.01). Suffering from one metabolic disease increased the risk of developing other metabolic diseases simultaneously.
Conclusion: From 2009 to 2023, the prevalence of major chronic metabolic diseases among adults has shown a significant increasing trend, with differences in age, gender, urban-rural areas, and regions.
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http://dx.doi.org/10.19813/j.cnki.weishengyanjiu.2024.06.005 | DOI Listing |
Brain Struct Funct
December 2024
State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Microglia play important roles in maintaining homeostasis and immunoreactive defense in the central nervous system including retina. To accomplish such a wide range of functions, microglia are highly heterogeneous. Dark microglia (DM) were recently identified by electron microscopy (EM).
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Design: Model development in 783 men with impaired glucose tolerance but not type 2 diabetes from T4DM; a multicenter, 2-year trial of Testosterone vs placebo.
Inflamm Bowel Dis
December 2024
Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Background: The consumption of ultra-processed foods has increased significantly worldwide and is associated with the rise in inflammatory bowel diseases. However, any causative factors and their underlying mechanisms are yet to be identified. This study aimed to further elucidate whether different types of the dietary emulsifier carrageenan (CGN) can alter the permeability and inflammatory state of the intestinal epithelium.
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January 2025
NYU Langone Health, New York, New York, USA.
Background: Chronic hepatitis B virus (HBV) infection is a common but underdiagnosed and undertreated health condition and is the leading cause of hepatocellular carcinoma (HCC) worldwide. HBV (rated a Grade 1 carcinogen by the International Agency for Research on Cancer) drives the transformation of hepatocytes in multiple ways by inducing viral DNA integrations, genetic dysregulation, chromosomal translocations, chronic inflammation, and oncogenic pathways facilitated by some HBV proteins. Importantly, these mechanisms are active throughout all phases of HBV infection.
View Article and Find Full Text PDFLiver Int
January 2025
Depatrtment of Medicine, Karsh Division of Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Background: The increasing prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), parallels the rise in sedentary lifestyles. MASLD is the most common form of steatotic liver disease (SLD), which represents the umbrella beneath which the vast majority of chronic liver diseases fall, including alcohol-related liver disease and their overlap. These conditions are the leading contributors to chronic liver disease, significantly impacting global morbidity and mortality.
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