Measles or rubeola is caused by an enveloped single-stranded RNA virus belonging to the genus Morbillivirus in the Paramyxoviridae family. Here, we present five adult measles patients. The laboratory confirmation of measles by serology/polymerase chain reaction (PCR) was carried out in the National Measles Laboratory as per WHO standard operating procedure at the Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. All of the patients presented with prodromal fever with rash. Diffuse erythematous maculopapular rash in a centrifugal manner was present. Measles was diagnosed based on clinical examination findings and positive serology or PCR reports from throat swab specimens. Two patients had a history of exposure; other patients denied any exposure. All of the patients were admitted and managed conservatively in the isolation ward during the period of infectivity.
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http://dx.doi.org/10.4269/ajtmh.24-0057 | DOI Listing |
Vaccine
January 2025
Centre for Immunization Surveillance and Programs, Infectious Disease and Vaccine Program Branch, Public Health Agency of Canada, 130 Colonnade Rd S, Nepean, ON K1A0K9, Canada; Department of Pediatrics, Faculty of Medicine, McGill University. Electronic address:
Background: In susceptible individuals, post-exposure prophylaxis (PEP) is often recommended following exposure to measles, however the data that these recommendations are based on are limited. The objective of this systematic review was to evaluate the efficacy/effectiveness and safety of immunoglobulins (Ig) or measles-containing vaccine (MCV) for the prevention of measles.
Methods: Prospective studies evaluating the use of Ig or MCV as PEP in susceptible individuals exposed to measles were eligible for inclusion.
Vaccines (Basel)
December 2024
National Centre for Epidemiology, Institute of Health Carlos III, 28029 Madrid, Spain.
Background/objectives: Spain has been in a measles elimination phase since 2014. No evidence exists about the distribution of measles cases among the population born outside Spain. The aim of this study was thus to describe the epidemiological situation of measles, stratified by place of birth, during the post-elimination period in Spain.
View Article and Find Full Text PDFFront Public Health
January 2025
Gwangju Center for Infectious Diseases Control and Prevention, Gwangju, Republic of Korea.
Introduction: Measles remains a public health concern, particularly among populations with suboptimal vaccination coverage, including immigrants. Understanding the seroprevalence of measles antibodies in immigrant populations is essential to inform tailored vaccination strategies and reduce the risk of measles reintroduction.
Methods: This study evaluated measles IgG seroprevalence among 651 immigrants from 30 countries residing in Gwangju, South Korea.
Mikrobiyol Bul
October 2024
Dokuz Eylül University Faculty of Medicine, Department of Medical Microbiology, İzmir, Türkiye.
Measles, rubella, mumps and chickenpox infections are among the childhood diseases that can be prevented by vaccination. Healthcare workers are at greater risk of diseases transmitted through contact with patients' respiratory secretions, infected blood and body fluids. Students studying in the field of health are at the risk of encountering infectious diseases as much as healthcare personnel during their internship and practice experience in healthcare institutions during their education.
View Article and Find Full Text PDFTrop Med Int Health
December 2024
Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Background: Acute febrile illness is a common reason for seeking healthcare in low- and middle-income countries. We describe the diagnostic utility of a TaqMan Array Card (TAC) real-time polymerase chain reaction (PCR) panel for pathogen detection in paediatric and adult inpatients admitted with febrile illness.
Methods: In this prospective cohort study, we screened medical admissions for a tympanic temperature ≥38.
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