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Crude Oil-Induced Reproductive Disorders in Male Goldfish: Testicular Histopathology, Sex Steroid Hormones, and Sperm Swimming Kinematics.
J Appl Toxicol
December 2024
South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Vodňany, Czech Republic.
Crude oil contamination has been shown to impair reproduction in aquatic animals through carcinogenic and genotoxic properties. Here, we assessed the endocrine-disrupting function of crude oil on male reproductive system based on testicular histology, sex steroid hormones, and fertility endpoints in adult male goldfish (Carassius auratus), which were exposed to 0.02- to 2-mg/L crude oil for 21 days (Experiment #1) or to 5- to 250-mg/L crude oil for 9 days (Experiment #2).
View Article and Find Full Text PDFMetformin ameliorates vanadium pentoxide or gamma irradiation-stimulated hepatotoxicity in male rats via targeting endoplasmic reticulum stress-induced apoptosis.
Hum Exp Toxicol
December 2024
Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Introduction: This work aims to validate the ameliorative influence of metformin against endoplasmic reticulum stress (ERS)-prompted apoptosis caused by vanadium pentoxide (VO) or gamma-irradiation (γ-irradiation) in hepatic tissues of male rats.
Methods: There were six groups of rats: the control, metformin (100 mg/kg body weight, .), VO (12.
Vanadium exposure and kidney markers in a pediatric population: a cross-sectional study.
Pediatr Nephrol
December 2024
Unidad de Investigación en Salud en El Trabajo, Centro Médico Nacional "Siglo XXI", Instituto Mexicano Del Seguro Social (IMSS), Ciudad de Mexico, Mexico.
Background: Anthropogenic vanadium (V) emissions and exposure in the general population have recently increased. Experimental studies have shown that V is a nephrotoxic agent, but little is known about its effects on human kidney health. This work evaluated the association between urinary V concentrations with early kidney damage biomarkers and function in a pediatric population without any disease diagnosed.
View Article and Find Full Text PDFMetal contaminants in rice imported to Iran: A comprehensive assessment of carcinogenic and non-carcinogenic health risks.
J Trace Elem Med Biol
November 2024
Toxicology Centre, University of Saskatchewan, Saskatoon, SK S7N 5B3, Canada.
Article Synopsis
- Rice is a key food in Iran, with large imports from India and Pakistan, but these imports are found to contain dangerous levels of heavy metals that could harm health.
- A study tested 60 rice samples for 34 different metals, using advanced analysis methods, to evaluate potential health risks associated with consumption, particularly focusing on carcinogenic and non-carcinogenic metals.
- The results showed that certain samples exceeded safe metal limits, indicating a significant cancer risk for both adults and children, highlighting an urgent need for improved public health measures related to imported rice.
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