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Microglia heterogeneity during neuroinflammation and neurodegeneration in the mouse retina.
Brain Struct Funct
December 2024
State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Microglia play important roles in maintaining homeostasis and immunoreactive defense in the central nervous system including retina. To accomplish such a wide range of functions, microglia are highly heterogeneous. Dark microglia (DM) were recently identified by electron microscopy (EM).
View Article and Find Full Text PDFEstablishing the Research Priorities of ADHD Professionals: An International Delphi Study.
J Atten Disord
December 2024
Deakin University, Melbourne, VIC, Australia.
Objectives: To determine ADHD research priorities from the perspective of ADHD professionals internationally.
Method: A two-stage modified Delphi design was used. In Stage 1 (qualitative), participants listed research questions relating to ADHD that they perceived to be most important ( = 132).
Orbital and sinus rhabdomyosarcoma with concurrent central retinal artery occlusion: A case report.
World J Clin Oncol
December 2024
Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, Dongguan 523000, Guangdong Province, China.
Background: Both rhabdomyosarcoma (RMS) and central retinal artery occlusion (CRAO) are rare medical diseases, and their simultaneous occurrence in the same patient is extraordinarily uncommon. This study presents a comprehensive overview of the clinical manifestations, diagnostic imaging results, and therapeutic interventions of a patient with both conditions.
Case Summary: In this report, we present a 30-year-old male who presented with significant protrusion, pain and vision loss and was diagnosed with RMS in the orbit and sinus with CRAO.
One interesting and elusive two-coupled oscillator problem.
Neurobiol Sleep Circadian Rhythms
May 2025
Instituto de Biociências, Departamento de Fisiologia, Universidade de São Paulo, SP, Brazil.
Chronobiology experiments often reveal intriguing non-linear phenomena, which require mathematical models and computer simulations for their interpretation. One example is shown here, where the two circadian oscillators located in the eyes of the mollusk were isolated and measured . By maintaining one eye under control conditions and manipulating the period of the second eye, Page and Nalovic (1992) obtained a diversity of results, including synchronized and desynchronized eyes, associated to weak coupling and period differences.
View Article and Find Full Text PDFNew Fresnel lens loupe for nystagmus observation suitable for use by medical staff in emergency departments.
Int J Emerg Med
December 2024
Mejiro University Ear Institute Clinic, 320 Ukiya, Iwatsuki-ku, Saitama-shi, Saitama, 339-8501, Japan.
Background: Reduction of spontaneous nystagmus by fixation, a characteristic feature of peripheral nystagmus, is important for differentiating between peripheral and central vestibular disorders. In the emergency room, Frenzel goggles are recommended to observe spontaneous nystagmus for the differential diagnosis of acute vestibular syndrome. We developed a portable loupe with a Fresnel lens to observe nystagmus.
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