Background: Oxidative stress and neuroinflammation play critical roles in the pathogenesis of migraine, a neurovascular disease. Cryptoxanthin is a carotenoid known for its potent antioxidant and anti-inflammatory properties. However, the specific association between serum cryptoxanthin levels and migraine remains unclear. This study aims to evaluate the correlation between migraine and serum cryptoxanthin levels.
Methods: For this cross-sectional analysis, information was gathered from individuals ≥20 years who took part in the National Health and Nutrition Examination Survey from 2001 to 2004. Details information was collected on migraines, serum cryptoxanthin levels and various crucial factors. Multivariable logistic regression and restricted cubic spline regression analyses were performed to investigate the relationship between serum cryptoxanthin and the occurrence of migraines.
Results: The study included 8,645 participants, of whom 20.00%(1734/8645) experienced migraine. There was a nonlinear relationship ( < 0.001) between serum cryptoxanthin levels and migraine, which was depicted as an L-shaped curve. The occurrence rate of individuals with serum cryptoxanthin levels below 26.64 nmol/dL experiencing migraine was 0.976 (95% CI: 0.965∼0.987, <0.001).
Conclusion: In adults among the United States, increased levels of serum cryptoxanthin were associated with decreased risk of migriane with a turning point at around 26.64 nmol/dL in American adults. Further studys are needed to confirm our findings.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/1028415X.2024.2443092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association between serum cryptoxanthin levels and migraine in American adults: results from NHANES.
Nutr Neurosci
December 2024
Department of Pain Management, the First people's Hospital of YiBin, Yibin, People's Republic of China.
Background: Oxidative stress and neuroinflammation play critical roles in the pathogenesis of migraine, a neurovascular disease. Cryptoxanthin is a carotenoid known for its potent antioxidant and anti-inflammatory properties. However, the specific association between serum cryptoxanthin levels and migraine remains unclear.
View Article and Find Full Text PDFRelationship between serum carotenoids and telomere length in overweight or obese individuals.
Front Nutr
November 2024
Department of Emergency, The People's Hospital of Baoan Shenzhen, Shenzhen, China.
Background: Previous researches have demonstrated an association between carotenoids and elongated telomeres. Nonetheless, there is scant scientific evidence examining this relationship in individuals who are overweight or obese, a demographic more predisposed to accelerated aging. This study aims to elucidate the correlation between serum carotenoid concentrations and telomere length within this population group.
View Article and Find Full Text PDFAssociation between serum carotenoids and migraine in adults: a cross-sectional study from NHANES data.
Eur J Nutr
November 2024
Department of Neurology, Affiliated Yueqing Hospital of Wenzhou Medical University, No.338 Qingyuan Road, Yueqing, Zhejiang Province, 325600, China.
Article Synopsis
- A study investigated the link between serum carotenoids, known for their anti-inflammatory and antioxidant effects, and the risk of migraines in U.S. adults.
- Out of 7,744 participants, 20.6% reported having migraines, with higher serum levels of certain carotenoids (α-carotene, β-carotene, and lutein + zeaxanthin) linked to a lower risk of migraines.
- Results suggest that lower carotenoid levels might increase migraine risk, indicating the need for further research to explore if there's a causal relationship.
Impact of serum carotenoids on cardiovascular mortality risk in middle-aged and elderly adults with metabolic syndrome.
Front Nutr
November 2024
Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Article Synopsis
- Metabolic syndrome (MetS) is linked to issues like obesity, high blood pressure, and inflammation, especially in older adults, and has mixed connections to dietary antioxidants like carotenoids in relation to heart disease.
- A study analyzing data from over 6,600 participants aged 40 and up found an inverse relationship between serum lycopene levels (a type of carotenoid) and cardiovascular disease (CVD) deaths over a median follow-up of 16.8 years.
- The results showed that higher lycopene levels corresponded with a reduced risk of CVD mortality, while no significant associations were found for other carotenoids studied.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!