Risk factors affecting the success of single-stage laparoscopic choledocholithiasis treatment: a retrospective analysis.

Objective: Aim: To identify and evaluate the risk factors affecting the success of single-stage laparoscopic treatment for choledocholithiasis.

Patients And Methods: Materials and Methods: We performed a retrospective analysis of treatment of 139 patients who underwent single-stage laparoscopic CBD exploration and cholecystectomy from 2018 to 2024. Data were analysed by the use of multivariate logistic regression to identify significant predictors of negative outcomes.

Results: Results: Multivariate logistic regression identified advanced age, multiple stones, and preoperative cholangitis as significant negative predictors of procedural success. Age increased the odds of a negative outcome by 20,8% per year (OR 1,208 [95% CI 1,124-1,298]; p<0,001), and each additional stone increased the odds by 21,5% (OR 1,215 [95% CI 1,435-3,127]; p<0,001). Preoperative cholangitis was associated with a 5-fold increase in negative outcomes (OR 5,485 [95% CI 6,397-65,607]; p<0,001). Stone size and altered anatomy were not significantly associated with the procedural success.

Conclusion: Conclusions: Advanced age, multiple stones and preoperative cholangitis significantly impact on the success of single-stage laparoscopic choledocholithiasis treatment, increasing the probability of unsuccessful procedure. Incorporating these predictors into clinical practice can enhance patient care and procedural success. Preoperative imaging and intraoperative techniques are crucial for optimizing outcomes.