A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Attempt to read property "Count" on bool

Filename: helpers/my_audit_helper.php

Line Number: 3100

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Descending necrotizing mediastinitis complicating deep neck abscesses: clinical features and prognostic assessment in 45 ICU patients. | LitMetric

Purpose: To describe the clinical features and identify mortality risk factors in descending necrotizing mediastinitis (DNM) complicating deep neck abscesses (DNA) among patients admitted to the ICU.

Methods: A retrospective analysis was conducted on consecutive patients admitted to the ICU of a tertiary care public hospital. Data were collected from July 2017 to July 2024. A bivariate analysis of variables, along with a multiple logistic regression model, were performed to identify mortality risk factors.

Results: Forty-five patients with DNA complicated by DNM were admitted to the ICU, of whom 29 (58%) were men. The mean age was 49.8 ± 14 years. All underwent emergency neck and mediastinum debridement. Forty-one (91%) were admitted directly from the operating room. All DNAs were of odontogenic origin. In 36 patients (80%), the mediastinal infection extended below the tracheal carina. Thirty-nine patients (86.6%) required mechanical ventilation, and 25 (55.5%) presented with septic shock. The in-hospital mortality rate was 33.3%. Risk factors for mortality in the bivariate analysis included the total SOFA (Sequential Organ Failure Assessment) score, individual SOFA components (respiratory, hematologic, and cardiovascular), SAPS-3 (Simplified Acute Physiology Score-3), platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio. In the multivariate analysis, the number of neck surgical debridements performed during ICU stay and the SOFA respiratory component were independent predictors of mortality.

Conclusions: DNM complicating a DNA is a severe condition frequently associated with septic shock and multi-organ failure. Impaired oxygenation at admission and the number of neck wound debridements significantly influenced patient outcomes.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-024-09179-7DOI Listing

Publication Analysis

Top Keywords

descending necrotizing
8
necrotizing mediastinitis
8
complicating deep
8
deep neck
8
neck abscesses
8
clinical features
8
identify mortality
8
mortality risk
8
risk factors
8
dnm complicating
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!