AI Article Synopsis
- - The study evaluates the safety and effectiveness of thermal ablation techniques for treating primary thyroid cancer versus traditional surgical resection.
- - A systematic review of 21 comparative and 40 noncomparative studies found thermal ablation to be better regarding operative time, pain, cost, quality of life, and complications while achieving similar tumor reduction and recurrence rates.
- - The findings suggest that thermal ablation techniques could be a viable alternative to surgery for certain cases of primary thyroid cancer, with comparable oncologic outcomes over a follow-up period of more than three years.
Article Abstract
Background: This study aimed to evaluate the safety, efficacy, and oncologic outcomes of thermal ablation techniques, including radiofrequency, laser, and microwave ablation, in treating primary thyroid cancer compared with surgical resection.
Method: We conducted a systematic review and network meta-analysis, which included 21 comparative studies and 40 noncomparative studies.
Results: The three thermal ablation techniques showed significant superiority over surgical resection in terms of operative time, pain, cost, quality of life, and complications. Three years after the procedure, the tumor volume reduction and complete disappearance rates for the three thermal ablation techniques were similar, at approximately 99% and 93%-95%, respectively. The recurrence rate remained comparable (approximately 2%-3%) among the three thermal ablation techniques and surgical resection during a follow-up period exceeding 3 years.
Conclusions: The safety, efficacy, and oncologic outcomes of thermal ablation techniques may be acceptable and comparable to surgical resection for selected cases of primary thyroid cancer.
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| http://dx.doi.org/10.1002/hed.28029 | DOI Listing |
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