AI Article Synopsis
- Researchers utilized PCR to detect bacterial infections in pleural fluid from Alaska Native children with empyema, despite the cultures being negative.
- Out of 14 specimens tested, PCR successfully identified at least one bacterial organism in 79% (11 specimens).
- Streptococcus pneumoniae serotype 3 was found in six specimens, all from children who had received the 13-valent pneumococcal conjugate vaccine.
Article Abstract
We used polymerase chain reaction (PCR) to identify bacterial infections in culture-negative pleural fluid specimens from Alaska Native children hospitalized with empyema. PCR identified ≥1 organism in 11 (79%) of 14 specimens. Streptococcus pneumoniae serotype 3 was detected in six specimens; all six participants had received 13-valent pneumococcal conjugate vaccine.
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| http://dx.doi.org/10.1093/jpids/piae131 | DOI Listing |
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