Purpose: The purpose of this work was to determine the comfort performance of a toric, monthly, silicon hydrogel CL (lehfilcon A; TOTAL30 for Astigmatism) over a long day of wear.
Methods: This was a 1-month, 3-visit, prospective, single-arm study. Adult, 18- to 45-year-old CL wearers with good vision who were minimally symptomatic (CLDEQ-8 scores ≤12) were enrolled. Subjects were required to have astigmatism ranging from -0.75 D to -2.50 D in each eye and were required to wear the study CLs from about 8:00 AM until 12:00 AM each day. Comfort data with the study CL throughout the wear day were collected via text messaging.
Results: A total of 47 subjects who had a mean ± SD age of 29.5 ± 7.0 years were analyzed. Within a specified time point across the month of wear, CL comfort did not vary (all p-value ≥ 0.82), yet CL comfort did decrease across the wear day for all days evaluated (all p-value <0.001). Most subjects found their CLs to be comfortable with only 1.8% of subjects reporting an uncomfortable score at CL application and only 8.5% of subjects reporting an uncomfortable score after 16 hours of CL wear.
Conclusion: A high level of consistency and predictability in comfort was found within the first month of wearing lehfilcon A CLs. This suggests that patients with minimal CL-related discomfort at initial fitting of a lehfilcon A CL may likely tolerate longer wear time with minimal discomfort across the entire month of wear.
Clinical Trialsgov Id: NCT06052046.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662920 | PMC |
http://dx.doi.org/10.2147/OPTO.S490934 | DOI Listing |
Clin Optom (Auckl)
December 2024
Eminent Ophthalmic Services, LLC, Milledgeville, GA, USA.
Purpose: The purpose of this work was to determine the comfort performance of a toric, monthly, silicon hydrogel CL (lehfilcon A; TOTAL30 for Astigmatism) over a long day of wear.
Methods: This was a 1-month, 3-visit, prospective, single-arm study. Adult, 18- to 45-year-old CL wearers with good vision who were minimally symptomatic (CLDEQ-8 scores ≤12) were enrolled.
Clin Ophthalmol
October 2023
Sengi, Penniac, NB, Canada.
Purpose: To subjectively evaluate comfort with a daily disposable (delefilcon A for astigmatism) contact lens compared to other common weekly/monthly soft toric contact lenses in symptomatic wearers.
Methods: This open-label, single arm study enrolled current reusable soft toric lens wearers with minimum score of 12 on the contact lens dry eye (CLDEQ-8) questionnaire. Subjects were also administered the CLDEQ-8 after 1 replacement schedule of their optimized habitual toric lenses (2 to 4 weeks), and after 2 weeks of wear with delefilcon A toric daily disposable lenses (Dailies Total1 for Astigmatism; Alcon Vision LLC, Fort Worth, Texas).
Cont Lens Anterior Eye
October 2023
Eurolens Research, Division of Pharmacy and Optometry, The University of Manchester, Oxford Rd, Manchester M13 9PL, United Kingdom. Electronic address:
Purpose: To determine clinical performance and the 'Willingness To Pay' for toric vs. spherical soft contact lenses in an astigmatic population.
Methods: In the clinical study, subjects with binocular low to moderate astigmatism (-0.
Cont Lens Anterior Eye
June 2022
School of Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Queensland, Australia. Electronic address:
Purpose: To document contact lens prescribing trends in the United Kingdom over the past quarter of a century.
Methods: An annual survey of contact lens prescribing was conducted each year from 1996 to 2020, inclusive, by asking a random selection of optometrists and contact lens opticians to provide information relating to 10 consecutive contact lens fits between January and March.
Results: Over the 25 year survey period, 2,671 practitioners returned survey forms, reporting a total of 25,575 contact lens fits.
Cont Lens Anterior Eye
December 2016
Eurolens Research, University of Manchester, United Kingdom.
Purpose: To understand long-term contact lens prescribing habits of Canadian optometrists.
Methods: One thousand optometrists were surveyed annually from 2000 to 2015. Information was requested on the first ten patients examined after receiving the survey.
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