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Comprehensive insights of Sneddon syndrome: A clinical perspective. | LitMetric

Comprehensive insights of Sneddon syndrome: A clinical perspective.

J Cent Nerv Syst Dis

Faculty of Medicine, The Hashemite University, Zarqa, Jordan.

Published: December 2024

AI Article Synopsis

  • Sneddon's syndrome is a rare condition that leads to blood vessel blockages in the brain and skin discoloration known as livedo reticularis, mainly affecting middle-aged women.
  • This review highlights the importance of recognizing the symptoms for timely diagnosis and emphasizes that the condition requires a clinical diagnosis based on careful patient observation.
  • More research is needed to enhance understanding, improve early diagnosis, and find better treatment options for those affected by Sneddon's syndrome.

Article Abstract

Background: Sneddon's syndrome is a rare thrombotic vasculopathy characterized by the coexistence of both cerebrovascular events and livedo reticularis.

Objective: This review aims to raise awareness among physicians by discussing the whole clinical spectrum of the disease. Typically, Sneddon syndrome presents in middle-aged women with a cerebrovascular accident and a preexisting skin rash, which is livedo reticularis. Diagnosis is primarily clinical, relying on a high index of suspicion. Management focuses mainly on reducing the risk of cerebral infarctions and alleviating symptoms.

Conclusion: Further research is necessary to better understand the disease's nature, which will contribute to improving early diagnosis and optimal management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660069PMC
http://dx.doi.org/10.1177/11795735241308767DOI Listing

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