Food safety is a global challenge, with nearly 1 in 10 people worldwide falling ill each year from consuming contaminated food. The risk is particularly high in ready-to-eat (RTE) products, which are consumed without further cooking to eliminate harmful microorganisms. To address this, the University of Cordoba and the University of Bologna, in the framework of the EU-FORA programme, developed a training programme focused on quantitative microbial risk assessment (QMRA) for in RTE food processing chains, a significant public health concern due to its association with severe foodborne illnesses. The programme aimed to train the fellow in advanced food microbiology techniques, predictive modelling and comprehensive QMRA methodologies. The fellow gained hands-on experience with predictive microbiology models applied to real-world scenarios, particularly RTE meat and fish products. Activities included developing predictive models for microbial growth and conducting challenge tests to evaluate behaviour in various foods. Emphasising data collection and statistical analysis, the fellowship explores the dynamics of Listeria within the food supply chain. A case study on sliced cooked ham demonstrates QMRA's application, using Monte Carlo simulations to estimate Listeria concentrations at consumption, ultimately informing risk management strategies. This initiative aimed to increase the number of food safety risk assessment experts in Europe, thereby enhancing public health outcomes related to foodborne diseases.
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http://dx.doi.org/10.2903/j.efsa.2024.e221106 | DOI Listing |
JAMA Netw Open
December 2024
Hypertension Laboratory, Cardiovascular Disease Center of Guangdong Province, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Importance: Although cumulative evidence suggests that higher blood pressure (BP) and a greater burden of social determinants of health (SDOH) are associated with an increased risk of stroke, few studies have examined whether SDOH burden modifies the association between BP and stroke risk.
Objective: To evaluate whether the association between BP classification and stroke risk differs by SDOH burden among Chinese adults.
Design, Setting, And Participants: In this cohort study, analyses were conducted among 90 850 participants in the prospective subcohort of the China Patient-Centered Evaluative Assessment of Cardiac Events Million Persons Project, with recruitment from January 1, 2016, to December 31, 2020.
Environ Sci Pollut Res Int
December 2024
Department of Physical, Earth and Environmental Sciences, University of Siena, 53100, Siena, Italy.
Sewage sludge applications as soil amendment call for a proper ecological risk assessment due to unexpected delivery of toxic chemicals and materials. Standardized acute toxicity assays have proven to provide limited information in terms of potential hazard for soil organisms. Here, sublethal endpoints as physiological and tissue alterations were proposed as suitable tools for sewage sludge ecological risk assessment.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
December 2024
Department of Ophthalmology and Laboratory of Eye Research, Rabin Medical Center - Beilinson Hospital, Felsenstein Medical Research Center, 39 Jabotinski St., Petach Tikva, 49100, Israel.
Background: Diabetes poses a risk to diabetic keratopathy in up to two-thirds of patients. Insulin-degrading enzyme (IDE) is a protease that can break down insulin and several growth factors and may impair wound healing. Increased IDE levels have been found in fluid from diabetic skin ulcers.
View Article and Find Full Text PDFPulm Ther
December 2024
Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA.
Introduction: Asthma is a complex condition characterized by airway inflammation. Interleukin-6 (IL-6) plays a significant role in asthma pathogenesis through its effects on T cells and its association with pro-inflammatory responses. Both lung and circulating IL-6 levels are elevated in asthma.
View Article and Find Full Text PDFEnviron Geochem Health
December 2024
Departamento de Explotación y Prospección Minera, Escuela de Ingeniería de Minas, Energía y Materiales, Universidad de Oviedo, Independencia, 13, 33004, Oviedo, Spain.
The food chain of the Valdezogues River system is at considerable risk due to the presence of mercury in the environment and to intense bioaccumulation and biomagnification processes in some fish species, particularly in piscivorous. Moreover, the presence of mercury in fish is a reliable indicator of the presence of its most toxic form, methylmercury. Of interest is that selenium, when present together with mercury in food, represents a significant decrease in the risks related to the ingestion of methylmercury.
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