An enteroatmospheric fistula (EAF) is one of the most feared complications of damage control laparotomy. Its management is highly challenging, often requiring multiple surgeries and prolonged hospitalization. It is a serious condition, and despite significant improvements in mortality rates due to advancements in intensive care, the rate remains substantial. We describe the case of a 75-year-old male who presented to the emergency department with abdominal pain one day after being discharged from another hospital following an elective converted cholecystectomy. He underwent emergency median relaparotomy, revealing fecal peritonitis and jejunum leakage. Following the jejunal segmental resection with mechanical anastomosis, we chose to leave the abdomen open. Eight days later, an EAF was established, and the abdomen was classified as grade 4 according to Bjork (classification of 2016). To manage this complication a four-step technique was employed: latex condom-EAF anastomosis, fistula ring creation, negative pressure wound therapy (NPWT), and adaptation of an ostomy bag. Nine weeks later, the wound was fully healed, and the stoma completely matured. Several recent reports have discussed the treatment of this condition. Techniques employing a baby bottle nipple, silicon plug, and floating stoma have shown promising results. NPWT was considered to increase the risk of fistula formation for many years, but additional studies have demonstrated its safety. No gold standard therapy has been established for EAF treatment; therefore, decisions rely on the surgical staff's experience. This technique for effluent control in patients with a Björk grade 4 abdomen and established EAF is easily reproducible and safe.
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http://dx.doi.org/10.7759/cureus.74209 | DOI Listing |
Cureus
November 2024
General Surgery, Centro Hospitalar Barreiro Montijo, Barreiro, PRT.
An enteroatmospheric fistula (EAF) is one of the most feared complications of damage control laparotomy. Its management is highly challenging, often requiring multiple surgeries and prolonged hospitalization. It is a serious condition, and despite significant improvements in mortality rates due to advancements in intensive care, the rate remains substantial.
View Article and Find Full Text PDFFuture Microbiol
December 2024
Department of Pharmacy, Pharmaceutical Biology Laboratory, Universidade Estadual de Maringá, Maringá, Brazil.
Objectives: To evaluate the antifungal activity of extracts and compounds from against clinically relevant species, notably , and investigate possible mechanisms of action using electron microscopy and techniques.
Methods: Extracts and fractions of were obtained through turboextraction and partitioning, while the isolated compounds were previously purified. The ethyl acetate fraction (EAF) was characterized by HPLC.
Plant Sci
December 2024
Universidade de Vigo. Departamento de Bioloxía Vexetal e Ciencia do Solo, Facultade de Bioloxía, Vigo 36310, Spain; Instituto de Agroecoloxía e Alimentación (IAA), Universidade de Vigo, Campus Auga, Ourense 32004, Spain. Electronic address:
Pelargonic acid (PA) is a saturated fatty acid commonly found in several organisms, that is known for its phytotoxic effect and its use as bioherbicide for sustainable weed management. Although PA is already commercialised as bioherbicide, its molecular targets and mode of action is unknown according to the Herbicide Resistance Action Committee. Therefore, the aim of this work was focusing on the way this natural active substance impacts the plant metabolism of the model species Arabidopsis thaliana.
View Article and Find Full Text PDFHum Reprod
October 2024
Department of Public Health and Primary Care, Leuven University, Leuven, Belgium.
Study Question: How were the logbook and curriculum for the Nurses and Midwives Certification Programme of ESHRE developed?
Summary Answer: The logbook and corresponding curriculum for the ESHRE Nurses and Midwives Certification Programme were based on an extensive literature review, an international expert panel, and a survey of Belgian and Dutch nurses and midwives (N&M) working in reproductive medicine (RM).
What Is Known Already: ESHRE has been running a certification programme for N&M working in RM since 2015. To the best of our knowledge, clinical practice guidelines for nursing/midwifery care within RM are lacking as is consensus on role descriptors of N&M working in RM.
J Anim Sci
January 2024
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, China.
The present study aimed to investigate the impact of initiating alfalfa supplementation at either 14 d or 42 d of age on growth performance, blood parameters, rumen tissue gene expression, and epithelial microbiota in pre-weaning lambs. A total of 42 seven-day-old male Hu lambs (3.88 ± 0.
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