AI Article Synopsis
- Sulfamethoxazole/trimethoprim (SMX/TMP) is widely used to treat bacterial infections like UTIs and has applications for MRSA and pneumonia.
- Although hepatotoxicity is a rare side effect of this medication, it can lead to severe liver issues in some patients.
- A case study detailed a 43-year-old man who developed jaundice and elevated liver enzymes after taking Bactrim for UTI, but he recovered well after stopping the medication and receiving supportive care.
Article Abstract
Sulfamethoxazole/trimethoprim (SMX/TMP) is a commonly used antimicrobial agent for treating common bacterial infections such as urinary tract infection (UTI), combined with doxycycline for community-acquired methicillin-resistant (MRSA), and invaluable in pneumonia (PJP), previously classified as . Of its known adverse reactions, hepatotoxicity rarely comes to mind, but indeed, it is a recognized but very rare adverse reaction that may lead to liver failure in adults and even rarer in children. We present a case of hepatotoxicity in a 43-year-old male patient on no prior medication who developed jaundice and highly elevated liver enzymes one week after the administration of Bactrim for the treatment of UTI in association with prostatism, symptoms of decreased urinary force due to obstruction of flow through the prostate gland. He made a good recovery over several weeks with discontinuation of the medication and supportive care.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659648 | PMC |
| http://dx.doi.org/10.7759/cureus.74053 | DOI Listing |
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