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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661527 | PMC |
| http://dx.doi.org/10.1080/08998280.2024.2426922 | DOI Listing |
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[Accurate determination of three new antihypertensive drugs illegally added to food using ultra-high performance liquid chromatography-tandem mass spectrometry].
Se Pu
October 2024
Anhui Provincial Institute for Food and Drug Control, China National Center for Quality Inspection and Test of Agricultural-Avocation Processed Food, Hefei 230051, China.
Effective strategies are required to address food safety issues related to the illegal addition of antihypertensive drugs to food and claims of antihypertensive function. In this study, a novel ultra-high performance liquid chromatography-triple-quadrupole mass spectrometry (UHPLC-MS/MS) method was developed for the simultaneous determination of three antihypertensive drugs (azilsartan, candesartan cilexetil, and lacidipine) in 12 food matrices (pressed candies, solid beverages, alternative teas, tea drinks, biscuits, jellies, mixed liquors, oral liquids, medicinal teas, tablets, hard capsules, and soft capsules). Initially, mass spectrometry parameters, such as the collision energies of the three antihypertensive drugs, were optimized.
View Article and Find Full Text PDFIris melanoma in an Australian cohort.
Clin Exp Ophthalmol
November 2024
Oncogenomics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Background: To report the clinicopathological features and epidemiology of iris melanoma in Queensland, Australia.
Methods: This was a retrospective study of 86 patients with iris melanoma treated between 2001 and 2022 at the Queensland Ocular Oncology Service, Brisbane, Australia. Main outcome measures included demographics, clinical and phenotypic features, age-adjusted incidence and relative survival.
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