Shins are one of the most vulnerable bones in human body. Shin guards are evaluated by their effectiveness in reducing the force applied to the bone. In this study, a structural modified mechanical lumped model of the shin guard was developed to provide maximum force distribution using physical parameter change modification technique and genetic algorithm. Modal analysis and finite element methods were used to determine the dynamic behavior of the system in the frequency range of 0-3000 Hz. In this research, FE results had an encouraging agreement with those in experimental test with a Mean Absolute Error (MAE) found as 34.94. The results proposed two design zones to select the stiffness of the shin guard. The stiffnesses K and K were selected between the values in the design zones. For situation, K = 7.9 × 10 N/m and K = 6.3 × 10 N/m, the distribution parameter was equal to 76% and f = 1.87F, f = 0.71F f = 1.81F, meaning the force was effectively distributed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10439-024-03668-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Allergic Contact Dermatitis From Football Shin Guards in a Child With Atopic Dermatitis.
Contact Dermatitis
January 2025
Department of Medicine, University of Udine, School of Medicine, Udine, Italy.
Developing a Structurally Modified Mechanical Lumped Model of the Human Tibia and Shin Guard Using Modal Analysis.
Ann Biomed Eng
December 2024
Eco-Friendly Smart Ship Parts Technology Innovation Center, Pusan National University, Busan, Republic of Korea.
Shins are one of the most vulnerable bones in human body. Shin guards are evaluated by their effectiveness in reducing the force applied to the bone. In this study, a structural modified mechanical lumped model of the shin guard was developed to provide maximum force distribution using physical parameter change modification technique and genetic algorithm.
View Article and Find Full Text PDFSplit Probe-Induced Protein Translational Amplification for Nucleic Acid Detection.
ACS Appl Bio Mater
December 2024
Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Nucleic acid detection is important in a wide range of applications, including disease diagnosis, genetic testing, biotechnological research, environmental monitoring, and forensic science. However, the application of nucleic acid detection in various fields is hindered by the lack of sensitive, accurate, and inexpensive methods. This study introduces a simple approach to enhance the sensitivity for the accurate detection of nucleic acids.
View Article and Find Full Text PDFEfficacy and safety of pembrolizumab in patients with advanced urothelial carcinoma deemed potentially ineligible for platinum-containing chemotherapy: Post hoc analysis of KEYNOTE-052 and LEAP-011.
Cancer
January 2025
Division of Cancer Medicine, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Background: First-line pembrolizumab monotherapy is a standard of care for platinum-ineligible patients with advanced urothelial carcinoma (UC). No global standardized definition of platinum ineligibility exists. This study aimed to evaluate the efficacy and safety of pembrolizumab monotherapy in patients with UC who met various criteria for platinum ineligibility.
View Article and Find Full Text PDFSmall Molecule Detection with Ligation-Dependent Light-Up Aptamer Transcriptional Amplification.
ACS Appl Bio Mater
October 2024
Department of Nanobiotechnology, KRIBB School of Biotechnology, University of Science and Technology, Daejeon 34113, Republic of Korea.
ATP and NAD are small biomolecules that participate in a variety of physiological functions and are considered as potential biomarkers for disease diagnosis. In this study, we developed a ligation-dependent light-up aptamer transcriptional amplification assay for the sensitive and selective detection of ATP and NAD. This assay relies on a specific DNA ligase that catalyzes the ligation of a nicked DNA template in the presence of a specific small molecule.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!