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"Assembly Theory" in life-origin models: A critical review. | LitMetric

"Assembly Theory" in life-origin models: A critical review.

Biosystems

ProtoBioCybernetics & Protocellular Metabolomics, The Gene Emergence Project, The Origin of Life Science Foundation, Inc, USA. Electronic address:

Published: December 2024

Any homeostatic protometabolism would have required orchestration of disparate biochemical pathways into integrated circuits. Extraordinarily specific molecular assemblies were also required at the right time and place. Assembly Theory conflated with its cousins-Complexity Theory, Chaos theory, Quantum Mechanics, Irreversible Nonequilibrium Thermodynamics and Molecular Evolution theory- collectively have great naturalistic appeal in hopes of their providing the needed exquisite steering and controls. They collectively offer the best hope of circumventing the need for active selection required to formally orchestrate bona fide formal organization (as opposed to the mere self-ordering of chaos theory) (Abel and Trevors, 2006b). This paper focuses specifically on AT's contribution to naturalistic life-origin models.

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http://dx.doi.org/10.1016/j.biosystems.2024.105378DOI Listing

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