Brucella anthropi, an aerobic, glucose-nonfermenting gram-negative rod, is predominantly an opportunistic pathogen affecting immunosuppressed patients. This case report describes a 27-year-old woman with systemic lupus erythematosus who developed persistent B. anthropi bacteremia following a pregnancy termination. Despite her stable condition and minimal symptoms, including transient fever, blood cultures revealed persistent bacteremia. Initial treatment with ceftazidime was ineffective due to resistance, leading to a switch to ciprofloxacin, which ultimately resolved the bacteremia. This case underscores the challenges in identifying the source of infection in the absence of typical symptoms and highlights the importance of vigilance in monitoring for persistent bacteremia, even in clinically stable patients. Our findings suggest that symptom improvement does not guarantee the resolution of bacteremia, propose follow-up blood cultures to ensure effective management of B. anthropi bacteremia.
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http://dx.doi.org/10.1016/j.jiac.2024.102595 | DOI Listing |
J Infect Chemother
December 2024
Department of Infectious Diseases, Matsudo City General Hospital, Chiba, Japan.
Brucella anthropi, an aerobic, glucose-nonfermenting gram-negative rod, is predominantly an opportunistic pathogen affecting immunosuppressed patients. This case report describes a 27-year-old woman with systemic lupus erythematosus who developed persistent B. anthropi bacteremia following a pregnancy termination.
View Article and Find Full Text PDFCureus
April 2024
Department of Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.
is a non-fermenting, Gram-negative bacillus and an emerging opportunistic pathogen. We have isolated this organism from the blood cultures of two patients, a 53-year-old immunocompetent male presenting with an episode of mild fever post craniotomy and an 85-year-old male with chronic obstructive pulmonary disease (COPD) and urinary retention on an indwelling catheter. The organism was identified using VITEK 2 (bioMérieux, France).
View Article and Find Full Text PDFInfect Disord Drug Targets
May 2024
HCA Las Palmas/Del Sol Internal Medicine Program, El Paso, Texas, 79902, USA.
Background: Ochrobactrum anthropi spp. is a non-enteric, aerobic gram-negative bacillus that has been reported to cause sepsis and occasionally bacteremia in both immunocompetent and immunocompromised hosts. This bacterium is capable of surviving in various habitats, but due to its affinity for aqueous environments, is hypothesized to have an affinity for indwelling plastic devices and other foreign bodies.
View Article and Find Full Text PDFJ Lab Physicians
March 2023
Department of Lab Medicine, Manipal Hospital, Bangalore, Karnataka, India.
, due to its robust survival abilities, has been known to cause nosocomial and opportunistic infections, posing both diagnostic and therapeutic challenges. Low virulence, indolent clinical presentation, and lack of awareness on their clinical significance attribute to the underreporting of the same. We report two cases of bacteremia in oncology patients presented to us in a short span of 6 months, which indicates that such infections might be quite common in immunocompromised hosts.
View Article and Find Full Text PDFJ Glob Antimicrob Resist
June 2022
Department of Clinical Laboratory, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:
Obejectives: To explore the genomic characterization of an IMP-8-producing Ochrobactrum anthropic and give suggestions for the application of antibiotics.
Methods: In 2021, the infection caused by CRKP was under control after nearly three months of using CAV, however, carbapenem-resistant O. anthropi isolates were collected from a rectal swab sample of a patient with Lumbar Disc Herniation Postoperative Infection.
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