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Evaluating the prognostic value of radiomics and clinical features in metastatic prostate cancer using [Ga]Ga-PSMA-11 PET/CT.
Phys Eng Sci Med
January 2025
School of Physics, Mathematics and Computing, University of Western Australia, Crawley, WA, Australia.
Prostate cancer is a significant global health issue due to its high incidence and poor outcomes in metastatic disease. This study aims to develop models predicting overall survival for patients with metastatic biochemically recurrent prostate cancer, potentially helping to identify high-risk patients and enabling more tailored treatment options. A multi-centre cohort of 180 such patients underwent [Ga]Ga-PSMA-11 PET/CT scans, with lesions semi-automatically segmented and radiomic features extracted from lesions.
View Article and Find Full Text PDFEnvironmental factors inducing gastric cancer: insights into risk and prevention strategies.
Discov Oncol
January 2025
The Second Hospital of Lanzhou University, Lanzhou, 730030, China.
Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. Despite ongoing advancements in treatment methods, its high incidence and mortality rates remain concerning. Although progress in treating gastric cancer is encouraging, a more critical focus is on enhancing prevention efforts.
View Article and Find Full Text PDFAlgal lipids: A review on current status and future prospects in food processing.
J Food Sci
January 2025
Department of Post-Harvest Technology, Rani Lakshmi Bai Central Agricultural University, Jhansi, Uttar Pradesh, India.
The consumer demand for functional foods derived from natural sources has been enhanced due to health-promoting effects. Algae are widely available globally as a sustainable source of proteins, lipids, and carbohydrates. Algal lipids are underexplored natural sources that exhibit several nutraceutical effects and applications in fortification, cosmetics, and pharmaceuticals.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) impacts over 50 million individuals and imposes a substantial burden on patients, caregivers, and society at large. Recent research suggests that AD is a continuum comprising preclinical, prodromal, and dementia stages, with underlying pathology manifesting well before symptoms appear. Early and accurate diagnosis is therefore crucial for optimal clinical outcomes; yet current diagnostic methods, such as neuroimaging and cerebrospinal fluid lumbar puncture, are expensive and invasive.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Seoul National University Bundang Hospital, Seongnam, Korea, Republic of (South).
Background: To investigate the neuroanatomical characteristics at the whole-brain level associated with progression from amyloid-positive preclinical to prodromal Alzheimer's disease (AD) in relation to amyloid deposition and regional atrophy.
Method: We included 45 participants with amyloid-positive preclinical AD and 135 participants with prodromal AD matched 1:3 by age, sex, and education, from participants in the Korean Longitudinal Study on Cognitive Aging and Dementia and visitors to the dementia clinic of Seoul National University Bundang Hospital. All participants underwent F-florbetaben positron emission tomography and 3D structural T1-weighted magnetic resonance imaging.
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