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Combined liver-kidney transplantation: 40 years of saving lives.
Lancet
December 2025
Experimental Center of BIOQGene, YuanDong International Academy Of Life Sciences, Hong Kong Special Administrative Region, China; Systems Biology Research Center, Biology Institute, Guangxi Academy of Sciences, Nanning, China.
Clinical Practice Recommendations on Kidney Management in Methylmalonic Acidemia: an Expert Consensus Statement From ERKNet and MetabERN.
Kidney Int Rep
December 2024
Division of Metabolic Diseases and Hepatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Methylmalonic acidemias (MMAs) are rare inherited metabolic diseases with multiorgan involvement. Chronic kidney disease (CKD) is a common complication, leading to kidney failure, dialysis, and kidney transplantation (KT). The objective of these guidelines was to develop clinical practice recommendations focusing on specific aspects of the kidney management of this disease.
View Article and Find Full Text PDFEvaluation of the toxic effects of food additives, alone or in mixture, in four human cell models.
Food Chem Toxicol
December 2024
Toxalim, INRAE, INP-ENVT, INP-EI-Purpan, Université de Toulouse 3 Paul Sabatier, Toulouse, France; Nutrition And Cancer Research Network (NACRe Network), France. Electronic address:
Food additives are present in more than 50% of food products. Several studies have suggested a link between the consumption of certain food additives and an increased risk of developing cancer. This study aimed to evaluate the genotoxicity of 32 additives and six mixtures identified by the NutriNet-Santé cohort as the most widely consumed.
View Article and Find Full Text PDFSingle and combined effect of chrysin and N-acetylcysteine against deltamethrin exposure in rats.
Food Chem Toxicol
December 2024
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey. Electronic address:
Effects of chrysin and N-acetylcysteine on deltamethrin exposure in rats were investigated. Eighty male Wistar Albino rats, weighing between 150 and 200 g and aged 2-3 months, were used and evenly allocated into eight groups. The control group of rats received a corn oil vehicle.
View Article and Find Full Text PDFThe Effectiveness of Levamisole and Broccoli in Lead Poisoning: Hematobiochemical Changes and Tissue Damage in the Liver, Kidney, and Spleen of Wistar Rats.
J Toxicol
November 2024
Department of Pathobiology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Lead, a heavy metal, has emerged as one of the most significant pollutants, bearing irreversible consequences on human and animal health in conjunction with industrial development. Presently, the use of medicinal plants to alleviate the adverse effects of heavy metal toxicity has captured the attention of researchers. Hence, the objective of this study was to assess the impact of levamisole and broccoli extract on the electrophoretic pattern of serum proteins, hematological parameters, and histopathological alterations in the liver, kidney, and spleen tissues within a lead poisoning model of rats.
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