Hypopituitarism and COVID-19, what else?

Pituitary

Department of Internal Medicine, General Hospital 71, Mexican Social Security Institute, Veracruz, Mexico.

Published: December 2024

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http://dx.doi.org/10.1007/s11102-024-01473-1DOI Listing

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Hypopituitarism and COVID-19.

Pituitary

December 2024

Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Purpose: This review aims to collect and examine recent research findings regarding hypopituitarism and COVID-19, focusing on the virus's impact on the pituitary gland and the outcomes for infected patients with hormonal deficiencies.

Methods: Literature review using PubMed (pubmed.ncbi.

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Purpose: Pituitary apoplexy (PA) has been increasingly reported in association with both infection from and vaccination for COVID19. Our aim was to analyse the available published cases and compare the clinical characteristics in the two groups (infection vs vaccination).

Methods: We systematically reviewed the published literature for all cases of PA associated with COVID19 infection or vaccination.

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Article Synopsis
  • This systematic review investigates recent cases of hypophysitis—an inflammation of the pituitary gland—in patients who have recovered from COVID-19.
  • Seven cases were studied, mainly involving young adults, with symptoms like headaches and increased thirst, emerging 2-3 weeks after COVID-19 symptoms.
  • The findings showed various imaging results, with some patients receiving glucocorticoid treatment, but long-term follow-up data was limited, highlighting the rarity and unique presentation of COVID-related hypophysitis.
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