A fraction of patients (approximately 10%) undergoing heart transplantation require permanent pacemaker (PPM) implantation due to sinus node dysfunction or atrioventricular block, occurring either shortly after surgery or later. The incidence of PPM implantation has declined to less than 5% with the introduction of bicaval anastomosis transplantation surgery. Pacing dependency during follow-up varies among recipients. A smaller subset (1.5-3.4%) receives implantable cardioverter-defibrillators (ICDs), but data on their use in transplant recipients are limited, primarily from cohort studies and case series. Sudden cardiac death affects around 10% of transplant recipients, attributed to various nonarrhythmic factors such as acute rejection, late graft failure, and cardiac allograft vasculopathy-induced ischemia. This review offers a comprehensive analysis of the existing data concerning the role of PPMs and ICDs in this population, encompassing leadless PPMs, subcutaneous ICDs, unique considerations, and future directions.
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http://dx.doi.org/10.1097/CRD.0000000000000817 | DOI Listing |
Cardiol Rev
November 2024
Department of Cardiovascular Medicine, Cardiovascular Analytics Group, Islamabad, Pakistan.
A fraction of patients (approximately 10%) undergoing heart transplantation require permanent pacemaker (PPM) implantation due to sinus node dysfunction or atrioventricular block, occurring either shortly after surgery or later. The incidence of PPM implantation has declined to less than 5% with the introduction of bicaval anastomosis transplantation surgery. Pacing dependency during follow-up varies among recipients.
View Article and Find Full Text PDFHeart Rhythm
December 2024
Quebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.
Background: There is a large variability regarding the management of conduction disturbances (CDs) after TAVR.
Objectives: To validate a pre-specified algorithm for managing CDs in patients undergoing TAVR.
Methods: Prospective multicenter study including consecutive patients without prior pacemaker undergoing TAVR.
Int J Biol Macromol
December 2024
Interdisciplinary Research Centre for Advanced Materials, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia; Department of Materials Science and Engineering, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia. Electronic address:
Research on Mg-based implants has increased recently because of their compatibility and biodegradability. Despite this promise, challenges related to high corrosion rates hampered wide-scale deployment. This paper explores the inhibiting properties of biomacromolecules, sodium alginate (ALG), hydroxyethyl cellulose (HEC), aspartame (ASP), and poly(ethylene oxide)-b-poly(propylene oxide) copolymer (PEO-b-PPO) on AZ31 Mg alloy in simulated body fluid at 37 °C.
View Article and Find Full Text PDFStruct Heart
November 2024
Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Background: Baseline right bundle branch block (RBBB) is an established predictor of permanent pacemaker (PPM) requirement after transcatheter aortic valve replacement (TAVR). There are limited data to support prophylactic PPM implantation in advance of TAVR. We aimed to evaluate the efficacy and safety of prophylactic PPM implantation in patients with RBBB prior to TAVR, and to identify the predictors of pacing dependence after TAVR.
View Article and Find Full Text PDFJACC Asia
November 2024
Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
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