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Filename: controllers/Detail.php
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Citrate is a potential biomarker for early stage detection of prostate cancer (PC), its concentration significantly dropped to 2-20 mM in PC patients. Herein, a cheap, simple, and reliable citrate sensor was proposed based on the biogenic synthesis of nitrogen-doped carbon dots (N-CDs) derived from the biowaste of Syzygiumcumini (S. cumini) seeds. The prepared N-CDs were characterized by TEM, FT-IR and spectral studies. The average size of the N-CDs was found to be 2.4 nm, the presence of -OH and -NH functional groups on the surface of N-CDs was confirmed by FT-IR analysis. The N-CDs possess the highest emission at 414 nm and cause quenching after reacting with citrate, which is due to the possible hydrogen bonding interactions between the probe and citrate. The probe expressed the lowest limit of detection of 3.5 nM, high selectivity, high interfering ability (1000-fold), provided a stable response at 5 min of reaction time, good biocompatibility, and delivered a contrast bioimage with different concentrations of citrate. The N-CDs were utilized to detect citrate in human urine samples, obtained good recovery results, and validated with the high-performance liquid chromatography method.
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http://dx.doi.org/10.1016/j.saa.2024.125568 | DOI Listing |
Heliyon
December 2024
Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
The extensive use of azo dyes in textile and pharmaceutical industries pose significant environmental and health risks. This problem requires to be tackled forthwith through a cheap, environmentally friendly and viable approach to mitigate water pollution. In this context, the green synthesis method was used for synthesis of ZnO NPs.
View Article and Find Full Text PDFMicrob Cell Fact
December 2024
Botany and Microbiology Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
This comprehensive review explores the emergence of titanium dioxide nanoparticles (TiO-NPs) as versatile nanomaterials, particularly exploring their biogenic synthesis methods through different biological entities such as plants, bacteria, fungi, viruses, and algae. These biological entities provide eco-friendly, cost-effective, biocompatible, and rapid methods for TiO-NP synthesis to overcome the disadvantages of traditional approaches. TiO-NPs have distinctive properties, including high surface area, stability, UV protection, and photocatalytic activity, which enable diverse applications.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Endocrinology and Metabolism, The Affiliated Hospital of Jiangsu University, Zhenjiang 212013, PR China; Institute of Endocrine and Metabolic Diseases, Jiangsu University, Zhenjiang 212013, PR China. Electronic address:
Citrate is a potential biomarker for early stage detection of prostate cancer (PC), its concentration significantly dropped to 2-20 mM in PC patients. Herein, a cheap, simple, and reliable citrate sensor was proposed based on the biogenic synthesis of nitrogen-doped carbon dots (N-CDs) derived from the biowaste of Syzygiumcumini (S. cumini) seeds.
View Article and Find Full Text PDFJ Pharm Biomed Anal
December 2024
Institute of Biomolecular Chemistry ICB, CNR, Traversa La Crucca 3, Regione Baldinca, Li Punti, Sassari 07100, Italy. Electronic address:
N-(3-hydroxyacyl)glycines are compounds of remarkable interest due to their biogenic origin and bioactivity and as precursors of the corresponding 3-acyloxy derivatives which represent an important class of bioactive products of bacterial origin. Commendamide [N-(3-hydroxypalmitoyl)glycine] (1) is a gut microbiota-derived bioactive metabolite that is structurally like endogenous long-chain N-acyl-amino acids belonging to the endocannabinoidome, a complex lipid signaling system involved in several aspects of mammalian physiology and pathology. Thanks to this structural similarity, this compound and its analogues, like the N-(3-hydroxymyristoyl)glycine 2, exert a remarkable bioactivity in mammals, for instance, through activation of G-protein-coupled receptors (GPCRs).
View Article and Find Full Text PDFWaste Manag
December 2024
Innovation Centre for Environment and Resources, Shanghai University of Engineering Science, No.333 Longteng Road, Songjiang District, Shanghai 201620, China. Electronic address:
Bio-based and biodegradable (bio-)plastics are heralded as a key solution to mitigate plastic pollution and reduce CO emissions. Yet, their end-of-life treatments embodies complex energy and material interactions, potentially leading to emissions through incineration or recycling. This study investigates the cradle-to-grave, emphasizing the waste management stage, carbon footprint for several types of bio-plastics, leveraging both GWP100a and CO uptake methods to explore the carbon reduction benefits of recycling over disposal.
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