Adult-child caregivers encounter various challenges due to their array of roles and tasks, often leading to a substantial sense of treatment burden. While previous research has explored factors contributing to treatment burden, much of it has centered on routine periods, leaving a gap in the understanding of this issue during crisis situations characterized by heightened stress and uncertainty. Therefore, this study aims to address this gap by investigating the mediating role of intolerance of uncertainty and war-related stress in the relationship between perceived social support and treatment burden among adult-child caregivers during the Israel-Hamas war. The study involved Israeli adult-child caregivers who completed a structured questionnaire distributed online. The findings showed that perceived social support was negatively associated with intolerance of uncertainty, which, in turn, was positively associated with war-related stress. Consequently, a positive correlation was observed between war-related stress and treatment burden. Perceived social support was found to be negatively associated with war-related stress. These findings underscore the significance of social support in reducing treatment burden, particularly during periods of heightened stress such as wartime. Understanding the interplay between these factors can inform the development of effective interventions aimed at alleviating the burden experienced by adult-child caregivers.
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http://dx.doi.org/10.1080/01634372.2024.2442013 | DOI Listing |
Lancet Psychiatry
December 2024
Background: High-quality estimates of the epidemiology of the autism spectrum and the health needs of autistic people are necessary for service planners and resource allocators. Here we present the global prevalence and health burden of autism spectrum disorder from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 following improvements to the epidemiological data and burden estimation methods.
Methods: For GBD 2021, a systematic literature review involving searches in PubMed, Embase, PsycINFO, the Global Health Data Exchange, and consultation with experts identified data on the epidemiology of autism spectrum disorder.
Eur J Med Res
December 2024
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Markos University, 269, Debre Markos, Ethiopia.
Background: Antibiotic resistance (AMR) remains a global public health threat with a high burden in sub-Saharan countries. The overuse of antimicrobials in the clinical setting is the main factor for the spread of antibiotic resistance. Diagnostic uncertainty in differentiating between bacterial and viral infections is the major contributor to antimicrobial overuse.
View Article and Find Full Text PDFJ Eat Disord
December 2024
School of Social Sciences, Arts Design and Architecture, University of New South Wales, Sydney, Australia.
Purpose: To examine autonomy within treatment and recovery from longstanding and severe eating disorders (EDs).
Background: The typically early age of onset, high incidence, and prolonged duration of EDs, has a high personal, relational, and financial burden for people who experience them. Current treatment practices rely on the exertion of external control and influence which has profound impacts on people living with EDs as well as the relationship and interactions between them and their treating professionals.
Nurs Open
December 2024
School of Nursing, Johns Hopkins University, Baltimore, Maryland, USA.
Aim: To discuss the need to expand advanced practice nurse education in Sub-Saharan Africa as a strategic response to the impact of the COVID-19 pandemic.
Design: Discursive paper.
Method: Searching international literature in PubMed, CINAHL and Google Scholar databases, we explored the impact of COVID-19 in Sub-Saharan Africa and the advanced practice nurse role and education in the pandemic response.
Br J Pharmacol
December 2024
Toxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.
Background And Purpose: Alzheimer's disease (AD) is a widespread neurodegenerative condition characterized by amyloid-beta (Aβ) plaques and tau protein aggregates, leading to significant cognitive decline. Existing treatments primarily offer symptomatic relief, underscoring the urgent need for novel therapies that address multiple AD pathways. This study evaluates the efficacy of DK02, a hydroxyl chalcone derivative, in a scopolamine-induced dementia model in zebrafish, hypothesizing that it targets several neurodegenerative mechanisms simultaneously.
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