We investigated the potential role of pivmecillinam in the treatment of urinary tract infections in children. Among 351 children (0-6 years) with urinary tract infections, 83% could be treated with pivmecillinam following urine culture. Resistance was highest in infants (0-3 months) caused by the high prevalence of Enterococcus faecalis. This result emphasizes the necessity for developing a pediatric oral form of pivmecillinam.
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http://dx.doi.org/10.1097/INF.0000000000004524 | DOI Listing |
Expert Opin Pharmacother
December 2024
Faculty of Medicine, Suez Canal university, Ismailia, Egypt.
Introduction: Alpha-1 adrenergic receptor antagonist (α1-ARA) are well established treatment for benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS). Since BPH and erectile dysfunction (ED) are commonly concomitant conditions, the importance of addressing the potential role of α1-ARA in patients with ED is rising.
Methods: We systemically reviewed literature for studies that assessed erectile function (EF) indices in relation to α1-ARA use.
Eur Urol Oncol
December 2024
Helen Diller Family Cancer Center, University of California-San Francisco, San Francisco, CA, USA. Electronic address:
Enfortumab vedotin (EV) is used as monotherapy or combined with pembrolizumab in advanced urothelial carcinoma (aUC), but biomarker data associated with EV outcomes are limited. We identified 170 patients in the UNITE study who received EV monotherapy and had molecular biomarker data available. Outcomes for groups with and without a particular biomarker were compared using logistic regression (unadjusted) for the objective response rate (ORR), and a log-rank test and Cox proportional-hazard models (CPHMs) for progression-free survival (PFS) and overall survival (OS) from EV initiation.
View Article and Find Full Text PDFUrolithiasis
December 2024
Department of Urology, Oxford University Hospitals NHS Trust, Oxford, Oxfordshire, UK.
Purpose: To compare stone clearance and complications between a 'wide' (9 × 50 mm) and 'narrow' shockwave focus (6 × 28 mm) when undertaking shockwave lithotripsy (SWL) in patients with renal or ureteric stones.
Methods: Data from patients undergoing SWL using the dual focus Storz Modulith SLX-F2 lithotripter at a single centre were prospectively collected between February 2018 and September 2020. Patients were matched by stone size, location, and number of treatments.
Cell Mol Biol (Noisy-le-grand)
November 2024
Department of Nutrition & Dietetics, National University of Medical Sciences, Rawalpindi, Pakistan.
Iron fortification compounds are of special interest to treat iron deficiency anemia, however, the dose-response effects of these fortificants on liver and renal functions have not been extensively reported in human subjects. The present study determines the effects of prebiotics and iron fortificants on liver function tests (LFTs) and renal function tests (RFTs) among women of reproductive age (WRA). A double-blind randomized controlled trial was performed for the duration of 90 days.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
November 2024
Branch of Clinical Sciences, College of Medicine, University of Sulaimani, Sulaimani, Kurdistan Region of Iraq.
The RENAL nephrometry score (RNS) is a standardized approach for grading the complexity of renal masses, although it does not have a strong correlation with the perioperative outcomes of open partial nephrectomy. To address these issues, a modified RENAL has been proposed. The study's goal is to determine the usefulness of a modified RENAL nephrometry score in predicting perioperative outcomes after open partial nephrectomy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!