Clin Pract Cases Emerg Med
Christiana Care Health System, Department of Emergency Medicine, Newark, Delaware.
Published: November 2024
Introduction: Propofol is an anesthetic agent commonly used in emergency department (ED) procedural sedation. It is often preferred in orthopedic procedures because of its muscle-relaxing properties. Rarely, however, it can induce agitation and muscle hypertonicity.
Case Report: A 58-year-old man presented to the ED with a left ankle fracture-dislocation. Propofol was used to facilitate procedural sedation, but the patient became mildly agitated. Ketamine was used to achieve full induction, after which propofol was used again to facilitate muscle relaxation. Near the end of the procedure, the patient had opisthotonos and masseter spasm requiring bag-valve-mask ventilation and subsequent intubation. This reaction was ultimately attributed to adverse effects of the propofol.
Conclusion: While propofol is generally well tolerated, it can potentially cause agitation, hypertonicity, and other side effects such as muscle spasms and seizure-like activity. Acknowledging and preparing for these risks can potentially improve patient outcomes.
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http://dx.doi.org/10.5811/cpcem.21283 | DOI Listing |
Perioper Med (Lond)
January 2025
Department of Anesthesia, Characteristic Medical Center of Chinese People's Armed Police Force (PAP), Tianjin, China.
Background: We investigated the consistency and accuracy of the Index of Consciousness (IoC) and the Bispectral Index (BIS) in monitoring the sedative effect of ciprofol during the induction of general anesthesia. There is extensive literature that reports good consistency and correlations between the IoC1 and the BIS in reflecting the sedation levels induced by propofol and sevoflurane but not by ciprofol.
Objective: The aim was to compare the consistency and accuracy of the IoC and BIS in monitoring the sedative effect of ciprofol during the induction of general anesthesia.
BMC Cancer
January 2025
Department of Anesthesiology, Harbin Medical University Cancer Hospital, 150 Haping Rd, Nangang District, Harbin, Heilongjiang, 150081, China.
Background: Different anesthetic drugs and techniques may affect survival outcomes for gastric cancer (GC) after surgery. In this study, we investigated the association between sedated and unsedated gastroscopy on survival outcomes in patients with GC after surgery.
Methods: This was a retrospective study of patients who were diagnosed with GC by gastroscopy and underwent gastrectomy from January 2013 to December 2017.
J Dent
January 2025
Clinic of General-, Special Care- and Geriatric Dentistry, Center for Dental Medicine, University of Zurich, Zurich, Switzerland. Electronic address:
Objectives: The study aimed to assess the prevalence and nature of emotional expressions in care-dependent older adults using an automated face coding (AFC) software. By examining the seven fundamental emotions, the study sought to understand how these emotions manifest and their potential implications for dental care in this population.
Methods: Fifty care-dependent older adults' (mean-age: 78.
Iran J Nurs Midwifery Res
November 2024
Department of Infectious Diseases, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: In patients with coronavirus disease 2019 (COVID-19), the incidence of delirium has been increased due to the nature of the disease and the specific protective protocols implemented to control the outbreak of this disease. The purpose of this study was to determine the effect of multidimensional nursing interventions on the incidence of delirium in patients with COVID-19.
Materials And Methods: A quasiexperimental study (preintervention, postintervention assessment) was conducted in168 patients (84 patients in each group) with COVID-19 admitted to the general wards of in , , between May and June 2021.
J Anaesthesiol Clin Pharmacol
March 2024
Department of Paediatric Surgery, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.
Background And Aims: Emergence delirium (ED) during the postanesthesia recovery phase presents significant challenges, especially among pediatric patients, with incidence rates spanning from 2% to 80%. This study sought to assess and compare the effectiveness of propofol and dexmedetomidine in addressing ED in pediatric patients undergoing sevoflurane anesthesia. The primary aim was to ascertain the prevalence of ED in both treatment cohorts, while secondary outcomes encompassed postoperative pain, hemodynamic responses, and the occurrence of complications.
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