Clinical pearls for the management of duloxetine patients with medical comorbidities.

Ment Health Clin

 Clinical Pharmacy Specialist, Psychiatry and Neurology, University of Michigan Health, Ann Arbor, Michigan; Clinical Associate Professor of Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan.

Published: December 2024

The effective use of duloxetine can be complicated by acute kidney injury, acute and/or chronic hepatic dysfunction, dysphagia, enteral nutrition, and common pharmacokinetic interactions. This article aimed to review the pharmacological properties of duloxetine pertinent to its use and to discuss the management of duloxetine in patients with common acute and chronic medical comorbidities. Management strategies based on clinical data and expert opinion are reviewed in 3 patient cases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616965PMC
http://dx.doi.org/10.9740/mhc.2024.12.313DOI Listing

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