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Reviving the Critically Ill: Exploring Effective Fluid Resuscitation Approaches for Diverse Hypovolemic Shock Cases-A Systematic Review and Meta-Analysis.
Bull Emerg Trauma
January 2024
Department of Emergency Medicine, Hamad Medical Corporation, Doha, Qatar.
Objective: The present study was performed to investigate the efficacy of different resuscitation fluids in critically ill patients presenting any type of hypovolemic shock.
Methods: We comprehensively searched PubMed, Web of Science, ScienceDirect, Cochrane Library, and Google Scholar for randomized trials published in English from January 1990 to August 2023. The risk of bias and methodological quality assessment was performed using Cochrane's risk of bias tool embedded within the Review Manager software (RevMan 5.
Comparative analysis of heart rate variability indices from ballistocardiogram and electrocardiogram: a study on measurement agreement.
Heart Vessels
December 2024
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Ballistocardiogram (BCG) captures minute vibrations generated by heart movements. These vibrations are converted into heart rate variability (HRV) indices, allowing their unobtrusive monitoring over extended periods, while reducing the burden on patients or subjects. In this study, to evaluate the agreement between the HRV indices, we compared the HRV indices estimated from the BCG device with those obtained from the gold standard electrocardiogram (ECG).
View Article and Find Full Text PDFSex differences in response to the endothelin receptor antagonist atrasentan in individuals with type 2 diabetes and chronic kidney disease: a post hoc analysis of the SONAR trial.
Diabetologia
December 2024
Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Aims/hypothesis: In the Study Of diabetic Nephropathy with AtRasentan (SONAR), the endothelin receptor antagonist (ERA) atrasentan slowed progression of chronic kidney disease (CKD) in individuals with type 2 diabetes. Pre-clinical research suggests sex-based differences in the endothelin system might influence the efficacy and safety of atrasentan. We therefore assessed the effects of atrasentan in men and women participating in SONAR.
View Article and Find Full Text PDFSex differences in the efficacy of angiotensin receptor blockers on kidney and cardiovascular outcomes among individuals with type 2 diabetes and diabetic kidney disease: post hoc analyses of the RENAAL and IDNT trials.
Diabetologia
December 2024
Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Aims/hypothesis: Our aim was to assess sex differences in the efficacy of angiotensin receptor blockers (i.e. losartan and irbesartan) on kidney and cardiovascular outcomes in individuals with type 2 diabetes and diabetic kidney disease.
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