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The need for adaptability in detection, characterization, and attribution of biosecurity threats. | LitMetric

The need for adaptability in detection, characterization, and attribution of biosecurity threats.

Nat Commun

Department of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, 1111 Engineering Dr, Boulder, CO, USA.

Published: December 2024

AI Article Synopsis

Article Abstract

Modern biotechnology necessitates robust biosecurity protocols to address the risk of engineered biological threats. Current efforts focus on screening DNA and rejecting the synthesis of dangerous elements but face technical and logistical barriers. Screening should integrate into a broader strategy that addresses threats at multiple stages of development and deployment. The success of this approach hinges upon reliable detection, characterization, and attribution of engineered DNA. Recent advances notably aid the potential to both develop threats and analyze them. However, further work is needed to translate developments into biosecurity applications. This work reviews cutting-edge methods for DNA analysis and recommends avenues to improve biosecurity in an adaptable manner.

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-024-55436-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659417PMC

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