Use of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Nodal Staging in Prostate Cancer and Tailoring of Treatment: A Continuing Conundrum.

Trials have shown that prostate-specific membrane antigen (PSMA)-based positron emission tomography/computed tomography (PET/CT) is more accurate than conventional imaging for staging of nodal status in prostate cancer. We discuss the advantages of PSMA PET/CT over current options for nodal staging and highlight the issues that need to be resolved for implementation of this modality in routine practice.