In 1859, the New Sydenham Society undertook the publication of an Atlas of Portraits of Diseases of the Skin, having been inspired by Ferdinand Ritter von Hebra's Atlas der Hautkrankheiten. Utilizing information contained in Sir Jonathan Hutchinson's Descriptive Catalogue of the New Sydenham's Society Atlas of Portraits of Diseases of the Skin (published in 1869 and 1875), an exhibit of twenty-five illustrations of cutaneous disorders, along with teaching points, was held at the Harvey Cushing/John Jay Whitney Medical Library at Yale University. It served as an educational tool for dermatologists, dermatology residents, medical students, and even physicians from other specialties.
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The New Sydenham Society's Atlas of Portraits of Diseases of the Skin - an Educational Tool.
Clin Dermatol
December 2024
Department of Dermatology, Yale School of Medicine, New Haven, CT.
In 1859, the New Sydenham Society undertook the publication of an Atlas of Portraits of Diseases of the Skin, having been inspired by Ferdinand Ritter von Hebra's Atlas der Hautkrankheiten. Utilizing information contained in Sir Jonathan Hutchinson's Descriptive Catalogue of the New Sydenham's Society Atlas of Portraits of Diseases of the Skin (published in 1869 and 1875), an exhibit of twenty-five illustrations of cutaneous disorders, along with teaching points, was held at the Harvey Cushing/John Jay Whitney Medical Library at Yale University. It served as an educational tool for dermatologists, dermatology residents, medical students, and even physicians from other specialties.
View Article and Find Full Text PDFSingle-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression.
Cell Death Dis
October 2021
Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences; Cancer Institutes; Key Laboratory of Breast Cancer in Shanghai; The Shanghai Key Laboratory of Medical Epigenetics; The International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology; Shanghai Medical College; Fudan University, 200032, Shanghai, China.
Breast cancer stem-like cells (BCSCs) play vital roles in tumorigenesis and progression. However, the origin and dynamic changes of BCSCs are still to be elucidated. Using the breast cancer mouse model MMTV-PyMT, we constructed a single-cell atlas of 31,778 cells from four distinct stages of tumor progression (hyperplasia, adenoma/MIN, early carcinoma and late carcinoma), during which malignant transition occurs.
View Article and Find Full Text PDFPoor prognosis of male triple-positive breast Cancer patients: a propensity score matched SEER analysis and molecular portraits.
BMC Cancer
May 2021
Department of Medical Oncology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.
Background: The purpose of this study was to explore clinicalpathology features, molecular features and outcome of male breast cancer patients who expressed ER, PR as well as HER-2, namely triple-positive male breast cancer (TP-MBC), and compared them with triple-positive female breast cancer patients (TP-FBC).
Methods: TP-MBC and TP-FBC from 2010 to 2017 were selected from the Surveillance, Epidemiology, and End Results database (SEER). Kaplan-Meier plotter and multivariable Cox regression model were applied to analyse the difference between TP-MBC and TP-FBC on cancer-specific survival (CSS) and overall survival (OS).
A pan-cancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy.
EJNMMI Res
April 2020
Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yongon-Dong, Jongno-Gu, Seoul, 110-744, Republic of Korea.
Purpose: Although somatostatin receptor (SST) is a promising theranostic target and is widely expressed in tumors of various organs, the indication for therapies targeting SST is limited to typical gastroenteropancreatic neuroendocrine tumors (NETs). Thus, broadening the scope of the current clinical application of peptide receptor radiotherapy (PRRT) can be supported by a better understanding of the landscape of SST-expressing tumors.
Methods: SST expression levels were assessed in data from The Cancer Genome Atlas across 10,701 subjects representing 32 cancer types.
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