Bacterial exopolysaccharides (EPS) are secondary metabolites of microorganisms which play important roles in adhesion, protection, biofilm formation, and as a source of nutrition. Compared with polysaccharides obtained from animal and plant species, bacterial polysaccharides have significant advantages in terms of production cost and large-scale production due to their abundant metabolic pathways and efficient polysaccharide production capacity. Most extracellular polysaccharides are water-soluble, and some are insoluble, such as bacterial cellulose. Some soluble bacterial EPS also have biological activities such as anticancer, antioxidant, antibacterial and immunomodulatory activities. These biological activities are mainly affected by the molecular weight, monosaccharide type, composition and structure of EPS. In recent years, bacterial EPS are considered as novel functional polysaccharides with important application prospects, especially in free radical scavenging and antioxidation. This review focuses on the characteristics of bacterial EPS, their ability to scavenge free radicals and their corresponding antioxidant mechanisms, and summarizes the relationship between different structures (such as monosaccharide composition, functional groups, molecular weight, etc.) and antioxidant activities. It provides a new idea for the development of more bioactive bacterial EPS antioxidants, points out a new direction for the commercial production of natural, safe and economical polysaccharide drugs and health products.
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http://dx.doi.org/10.1016/j.ijbiomac.2024.138849 | DOI Listing |
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