Characterization and evaluation of the adsorption of uremic toxins through the pyrolysis of pineapple leaves and peels and by forming a bio-complex with sodium alginate.

This study was performed to develop an optimal process for manufacturing activated carbon (AC) from pineapples' off-cuts (leaves and peels; PL and PP) by pyrolysis and for forming a bio-complex with sodium alginate (CA). In addition, the physicochemical properties were also explored under different preparation conditions, and the effects of adsorbed uremic toxins in three simulated gastrointestinal conditions (in vitro) were evaluated. This study showed that pyrolysis at 800 °C and activation by CO (30 min) resulted in satisfactory porous profiles with high specific surface areas of 388.79 and 536.84 m/g for PLAC and PPAC, respectively. Regarding appearance and microstructures, there are still discernible disparities compared to the AST in regular service, while it exhibits a similar peak shape to that of the AC under the Raman spectrometer. Remarkably, the adsorption capacity of PLAC and PPAC for uremic toxins was best for indole adsorption while providing a consistent effect with AST. Indole-3-acetic acid (3-IAA) and p-cresol (p-C) adsorption capacities were the second highest. Nevertheless, AST also exhibited varying degrees of reduced adsorption capacity under different gastrointestinal simulation conditions. Therefore, this study conditions the development of cost-effective adsorbent products targeting uremic toxins, which could generate novel synergistic systems based on pineapple by-products within the circular economy framework.