AI Article Synopsis
- * The review explores how this bacterium interacts with our body's cells and how it manages to stick around even when the immune system tries to fight it off.
- * It emphasizes the need for more research on these interactions to create better ways to prevent and treat infections linked to C. acnes.
Article Abstract
Cutibacterium acnes is a commensal Gram-positive anaerobic bacterium that can also act as an opportunistic pathogen in various diseases, particularly in prosthetic joint infections (PJI). Throughout this review, we delve into the current understanding of the intricate interactions between C. acnes and host cells and discuss bacterial persistence in the host. C. acnes colonization and subsequent PJI set-up represent complex processes involving bacterial adhesion, immune recognition, and host response mechanisms. We highlight existing knowledge and gaps in specific host-pathogen interactions and stress the importance of acquiring additional information to develop targeted strategies for preventing and treating C. acnes-related PIJ.
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| http://dx.doi.org/10.1016/j.resmic.2024.104265 | DOI Listing |
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