Neuronal activity and mitochondrial gene expression become decoupled in aged mice.
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Barriers and enablers encountered by bereaved informal motor neuron disease (MND) caregivers when trying to access bereavement support: a qualitative cross-sectional thematic analysis of semistructured interviews with 6-36 months postbereavement informal MND caregivers in the UK.
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Lancashire and South Cumbria MND Care and Research Centre, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Background: Caregivers of people with motor neuron disease (MND) face more negative consequences of caregiving than other terminal illnesses. The impact of this caregiver burden can negatively influence bereavement outcomes.
Objectives: This study aims to explore the support needs of caregivers of people with MND, the types of bereavement services they use, or the reasons for not using bereavement services, and understanding the opportunities and barriers to accessing bereavement services.
Pediatric Sleep Quality and Parental Stress in Neuromuscular Disorders: Descriptive Analytical Study.
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Nursing Care Research Center, Clinical Sciences Institute, Nursing Faculty, Baqiyatallah University of Medical Sciences, Vanak Square, Tehran, Iran, 98 9127297199.
Background: Neuromuscular disorders (NMDs) constitute a heterogeneous group of disorders that affect motor neurons, neuromuscular junctions, and muscle fibers, resulting in symptoms such as muscle weakness, fatigue, and reduced mobility. These conditions significantly affect patients' quality of life and impose a substantial burden on caregivers. Spinal muscular atrophy (SMA) is a relatively common NMD in children that presents in various types with varying degrees of severity.
View Article and Find Full Text PDFInflammatory microglia correlate with impaired oligodendrocyte maturation in multiple sclerosis.
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Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Amsterdam, Netherlands.
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Alzheimers Dement
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Introduction: Iron-mediated cell death (ferroptosis) is a proposed mechanism of Alzheimer's disease (AD) pathology. While iron is essential for basic biological functions, its reactivity generates oxidants which contribute to cell damage and death.
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