AI Article Synopsis
- Pancreatic cancer is deadly and often undetected until it's too late, mainly due to ineffective current diagnostic methods and treatments.
- Extracellular vesicles have been identified as promising biomarkers that could help in the early diagnosis and monitoring of pancreatic cancer via non-invasive liquid biopsies.
- This review discusses the various roles of extracellular vesicles in cancer progression and their potential as valuable tools for diagnosis, prognosis, and therapy specifically for pancreatic cancer.
Article Abstract
Pancreatic cancer is a highly lethal and metastatic malignancy, mainly because it often remains undetected until advanced stages due to the limitations of current diagnostic methods, rendering currently available therapies ineffective. Therefore, it is imperative to identify useful biomarkers for early diagnosis and new therapeutic targets for pancreatic cancer. Recently, extracellular vesicles have emerged as promising biomarkers for the diagnosis and prognosis of pancreatic cancer. Given their presence in various bodily fluids, extracellular vesicles offer a non-invasive approach through liquid biopsy to detect and monitor cancer progression. In this review, we comprehensively examine the multifaceted roles of extracellular vesicles in the progression of cancer, while also exploring their potential as diagnostic, prognostic, and therapeutic biomarkers in the context of pancreatic cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648502 | PMC |
| http://dx.doi.org/10.20517/evcna.2023.68 | DOI Listing |
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