Switzerland has been considered free of terrestrial rabies for more than 20 years. Nevertheless, the topics of rabies and rabies vaccination are more relevant than ever. On the one hand, this is because the demand for vaccines is increasing due to the increasing mobility of humans and animals, and on the other hand, there are frequent vaccine supply shortages. Our article highlights the key points in the face of growing challenges.
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[Rabies and mobility: 2025 update].
Praxis (Bern 1994)
December 2024
Zentrum für Reisemedizin der Universität Zürich, Departement Public Global Health, Institut für Epidemiologie, Biostatistik und Prävention, Universität Zürich | WHO Collaborating Centre for Travellers' Health, Zürich.
Switzerland has been considered free of terrestrial rabies for more than 20 years. Nevertheless, the topics of rabies and rabies vaccination are more relevant than ever. On the one hand, this is because the demand for vaccines is increasing due to the increasing mobility of humans and animals, and on the other hand, there are frequent vaccine supply shortages.
View Article and Find Full Text PDFA three-way interface of the Nipah virus phosphoprotein X-domain coordinates polymerase movement along the viral genome.
J Virol
October 2024
Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Unlabelled: Nipah virus (NiV) is a highly pathogenic paramyxovirus causing frequently lethal encephalitis in humans. The NiV genome is encapsidated by the nucleocapsid (N) protein. RNA synthesis is mediated by the viral RNA-dependent RNA polymerase (RdRP), consisting of the polymerase (L) protein complexed with the homo-tetrameric phosphoprotein (P).
View Article and Find Full Text PDFEvaluation of a real-time mobile PCR device (PCR 1100) for the detection of the rabies gene in field samples.
Trop Med Health
March 2023
Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Oita, Japan.
Background: The Philippines is ranked among the top countries with 200-300 annual deaths due to rabies. Most human rabies cases have been reported in remote areas, where dog surveillance is inadequate. Therefore, a strategy to effectively improve surveillance in remote areas will increase the number of detections.
View Article and Find Full Text PDFZoonoses as Important Causes of Hospital Admissions: A 15-Year Study in Portugal.
Port J Public Health
September 2022
CIISA, Centro Interdisciplinar de Investigação em Sanidade Animal, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
Introduction: Zoonoses represent 75% of emerging diseases. These diseases pose a permanent threat to human health and well-being and have the potential to become increasingly frequent due to habitat degradation; land-use changes; and increased global mobility of humans, animals, and animal products. The objective of this study was to investigate the impact ten zoonoses (brucellosis, cysticercosis, echinococcosis, leishmaniasis, leptospirosis, Lyme disease, rabies, toxoplasmosis, trichinellosis, and West Nile fever) had on human hospitalizations between 2002 and 2016 in Portuguese National Health Service hospitals.
View Article and Find Full Text PDFRabies in the Tropics.
Curr Trop Med Rep
March 2022
Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camden, NSW Australia.
Purpose Of Review: Rabies is an ancient yet still neglected tropical disease (NTD). This review focuses upon highlights of recent research and peer-reviewed communications on the underestimated tropical burden of disease and its management due to the complicated dynamics of virulent viral species, diverse mammalian reservoirs, and tens of millions of exposed humans and animals - and how laboratory-based surveillance at each level informs upon pathogen spread and risks of transmission, for targeted prevention and control.
Recent Findings: While both human and rabies animal cases in enzootic areas over the past 5 years were reported to PAHO/WHO and OIE by member countries, still there is a huge gap between these "official" data and the need for enhanced surveillance efforts to meet global program goals.
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