For the estimation of the health risks of radiation in man by low radiation doses as well as to compare the man-made radiation exposure with the natural one, it is proved useful and necessary to estimate the effective dose-equivalent. It is not sufficient to take only into consideration the radiation exposure of bone marrow and gonads. Due to an external irradiation source as well as by incorporation of radioactive materials, various tissues and organs in the human body will simultaneously be exposed. This is best illustrated by the component of the "natural" radiation exposure with radon, attributable more or less to our living conditions. The incorporation of radon and its daughters in the lung with its cancer causing risk is not evaluated in the determination of the gonads and bone marrow dose. The effective dose-equivalent is being estimated for the evaluation of possible radiation risk by the carcinogenic and mutagenic effectiveness of radiation (stochastic radiation risk) with weighting factors. For the genetic risk solely 25% and for the somatic risk 75% are granted, whereas the risk factor "breast tissue" dominates.
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BMC Cancer
January 2025
Department of Gynecology with Breast Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charité Universitätsmedizin Berlin, Berlin, Germany.
Background: In recent years, there has been a growing number of case reports documenting delayed seroma in patients with a history of breast surgery and reconstruction. The occurrence of these seromas has been associated with prior SARS-CoV-2 infection or SARS-CoV-2 vaccination. So far, there are few systematic analyses on postoperative complications in breast surgery since the emergence of the SARS-CoV-2 pandemic.
View Article and Find Full Text PDFAnn Surg Oncol
January 2025
Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Background: Preventative medication (PM) uptake is low among patients at an elevated risk of breast cancer, largely due to fears of intolerance. This study aimed to investigate whether a new, surgical advanced practice provider (APP)-run clinic was effectively prescribing PM. We hypothesized equivalent rates of PM uptake compared to consultation with medical oncologists (MD).
View Article and Find Full Text PDFGeroscience
January 2025
Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Aging is influenced by a complex interplay of multifarious factors, including an individual's genetics, environment, and lifestyle. Notably, high altitude may impact aging and age-related diseases through exposures such as hypoxia and ultraviolet (UV) radiation. To investigate this, we mined risk exposure data (summary exposure value), disease burden data (disability-adjusted life years (DALYs)), and death rates and life expectancy from the Global Health Data Exchange (GHDx) and National Data Management Center for Health of Ethiopia for each subnational region of Ethiopia, a country with considerable differences in the living altitude.
View Article and Find Full Text PDFSci Rep
January 2025
The Edgar L. and Harold H. Buttner Chair of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
The highly pathogenic avian influenza A(H5N1) virus threatens animal and human health globally. Innovative strategies are crucial for mitigating risks associated with airborne transmission and preventing outbreaks. In this study, we sought to investigate the efficacy of microwave inactivation against aerosolized A(H5N1) virus by identifying the optimal frequency band for a 10-min exposure and evaluating the impact of varying exposure times on virus inactivation.
View Article and Find Full Text PDFMed Dosim
January 2025
Department of Radiation Oncology, People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences, 530021, Nanning, Guangxi, China. Electronic address:
Axillary dose restriction (ADR) is rarely implemented in breast cancer radiotherapy by radiation oncologists to minimize exposure to organs at risk (OARs), particularly the axilla. This prospective randomized controlled study aims to evaluate the efficacy of ADR in improving plan quality (PQ) and its impact on acute radiation dermatitis (ARD) in breast cancer radiotherapy. The study recruited breast cancer patients who required postoperative radiotherapy but did not have an indication for axillary irradiation.
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