Stimulating localizable sensations.

Nat Biomed Eng

Departments of Neurology, Neuroscience and Biomedical Engineering, University of Rochester, Rochester, NY, USA.

Published: December 2024

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http://dx.doi.org/10.1038/s41551-024-01321-4DOI Listing

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Stimulating localizable sensations.

Nat Biomed Eng

December 2024

Departments of Neurology, Neuroscience and Biomedical Engineering, University of Rochester, Rochester, NY, USA.

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Tactile feedback from brain-controlled bionic hands can be partially restored via intracortical microstimulation (ICMS) of the primary somatosensory cortex. In ICMS, the location of percepts depends on the electrode's location and the percept intensity depends on the stimulation frequency and amplitude. Sensors on a bionic hand can thus be linked to somatotopically appropriate electrodes, and the contact force of each sensor can be used to determine the amplitude of a stimulus.

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  • Drug-resistant epilepsy (DRE) is tough to manage, but new treatments called neuromodulation can help those who don't respond to regular medicine.
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The overall objective of this study was to construct a 3D neuroanatomical map of the saphenous nerve based on cartesian coordinate data to define its course in 3D space relative to bony and soft tissue landmarks. Ten lower limb embalmed specimens were meticulously dissected, digitized, laser scanned, and modelled in 3D. The course of the main branches, number of collateral branches, and relationship of saphenous nerve to the great saphenous vein were defined and quantified using the high-fidelity 3D models.

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When we interact with objects, we rely on signals from the hand that convey information about the object and our interaction with it. A basic feature of these interactions, the locations of contacts between the hand and object, is often only available via the sense of touch. Information about locations of contact between a brain-controlled bionic hand and an object can be signaled via intracortical microstimulation (ICMS) of somatosensory cortex (S1), which evokes touch sensations that are localized to a specific patch of skin.

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