Forty hepatic abscesses were examined with dynamic computed tomography (CT). A "double target sign," consisting of a hypodense central area surrounded by first a hyperdense ring and then a hypodense zone, seems to be highly suggestive of abscess formation. In 12 cases, the hepatic parenchyma surrounding the lesion demonstrated transient hyperdensity after contrast injection, possibly due to localized hepatic venous obstruction secondary to acute hepatic inflammation. This is similar to the appearance of an arterioportal fistula.
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http://dx.doi.org/10.1148/radiology.154.3.3969480 | DOI Listing |
Front Pharmacol
February 2025
Department of Pharmacology, The First People's Hospital of Yancheng, Yancheng, Jiangsu, China.
Background: Ripretinib is a tyrosine kinase inhibitor indicated for the treatment of adult patients with advanced gastrointestinal stromal tumors (GISTs) who have previously received treatment with at least three kinase inhibitors. The objective of this study was to evaluate adverse events(AEs) associated with ripretinib using data from the FDA Adverse Event Reporting System (FAERS) database.
Methods: Individual case safety reports (ICSRs) related to of ripretinib from 2020 Q2 to 2024 Q2 were extracted from the FAERS database.
BMC Infect Dis
March 2025
Department of Emergency, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Background: Amoebic liver abscess is a hepatic infection due to the invasion of Entamoeba histolytica. This parasitic infection is globally distributed, particularly in tropical and subtropical regions. A remarkable decline in the incidence of amoebic liver abscesses has been observed in recent years thanks to economic and public health progress.
View Article and Find Full Text PDFJ Microbiol Immunol Infect
March 2025
Division of Infection, Department of Internal Medicine, Ministry of Health and Welfare Shuang-Ho Hospital, New Taipei City, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Microbiology, JIPMER, Puducherry, India.
Meliodosis is an infectious disease also called whitemore's disease that can be fatal and is caused by the bacteria . This facultative intracellular aerobic gram-negative bacterium is typically transmitted through direct contact with contaminated water or soil (Currie et al. in Seminars in Respiratory and Critical Care Medicine 36:111-125, 2015).
View Article and Find Full Text PDFCureus
February 2025
Gastroenterology, Icahn School of Medicine at Mount Sinai, Queens, USA.
Hepatolithiasis is a condition characterized by the presence of bile stones in the intrahepatic bile ducts. It represents a significant therapeutic challenge owing to its association with recurrent cholangitis, biliary obstruction, and potentially life-threatening complications such as hepatic abscesses and cholangiocarcinoma. Traditional treatments include hepatectomy and percutaneous transhepatic cholangioscopic lithotomy (PTCL), both of which are effective but highly invasive, whereas endoscopic approaches often leave residual stones.
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