AI Article Synopsis
- A school-aged boy with no prior health issues developed chronic dacryoadenitis (inflammation of the lacrimal glands) after experiencing mild respiratory symptoms and testing positive for SARS-CoV-2 three months earlier.
- MRI scans indicated swollen lacrimal glands, and histological analysis confirmed the diagnosis of bilateral chronic dacryoadenitis.
- The condition improved with topical steroids over two months, and although SARS-CoV-2 was found in inflammatory cells, PCR tests for the virus in lacrimal fluid were negative, suggesting a unique link between the virus and the eye condition.
Article Abstract
We report a case of chronic dacryoadenitis associated with SARS-CoV-2, confirmed by histological analysis. A previously healthy school-aged boy was admitted to the paediatric department with a 1 month history of both eyebrow swelling and very mild pain in the upper parts of both eyelids. Gadolinium-enhanced T1-weighted MRI revealed enlargement of both lacrimal glands. Clinicopathological analysis confirmed bilateral chronic dacryoadenitis. Topical steroids were given, resulting in slow resolution over 2 months, and clinical stability at 10 months. The patient had experienced mild respiratory symptoms and tested positive for SARS-CoV-2 antigen via PCR testing, diagnosed as SARS-CoV-2, 3 months prior to the onset of dacryoadenitis. Inflammatory cells around the lacrimal gland demonstrated immunoreactivity for SARS-CoV-2 nucleocapsid protein. However, PCR testing of lacrimal fluid for SARS-CoV-2 was negative. This case illustrates protean complications and suggests a probable pathogenetic mechanism of dacryoadenitis associated with SARS-CoV-2.
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| http://dx.doi.org/10.1136/bcr-2023-257615 | DOI Listing |
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