AI Article Synopsis
Article Abstract
Background: There is limited knowledge regarding how long prepared sterile goods can wait before becoming contaminated. We investigated whether surgical goods could be prepared the day before surgery and kept sterile overnight in the operating room, if protected by sterile covers.
Methods: Sterile surgical goods for open-heart surgeries (n=70) were randomized to preparation on the morning of the operation or on the previous evening. Exposure time was the total time between preparation and use. Primary outcome was bacterial growth reported as colony forming units (cfu), isolated on 840 agar plates. The protocol was registered with ClinicalTrials.gov (NCT05597072).
Results: When the agar plates were protected with sterile covers, exposure time had no impact (intervention group: 7 cfu, control group: 17 cfu). Without protection, longer exposure time was associated with more cfu (p=0.016). A total of 499 cfu were isolated, displaying 59 different types of bacteria including 13 resistant Staphylococcus epidermidis, 6 (46%) of which were multidrug resistant.
Conclusions: Sterile goods could wait in the operating room for at least 15 hours before use without increased risk of bacterial air contamination, if protected with sterile covers. However, if the goods were not covered, bacterial air contamination occurred over time.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajic.2024.12.012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
detected in pleural effusion fluid: A case report.
Biomed Rep
February 2025
Department of Laboratory Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi 046000, P.R. China.
is predominant in dental caries and is commonly observed in patients with oral diseases; however, its presence in patients with pleural effusion remains rare. Pleural effusion can arise from various causes, including malignant tumors, tuberculosis and bacterial infections. Concurrent infections involving bacteria, fungi and are infrequent.
View Article and Find Full Text PDFStudy of the synergistic properties of copaiba oil co-electrospun with poly(L-co-D,L lactic acid) and natural rubber latex for application in bioactive wound dressings.
Int J Biol Macromol
December 2024
Post-Graduation Program in Materials Sciences (PPGCM), Federal University of São Carlos (UFSCar), 18052-780, Brazil; Laboratory of Biomaterials, Faculty of Medical Sciences and Health (FCMS), Pontifical Catholic University of São Paulo (PUC-SP), 18030-070, Brazil; Mechanical Engineering Faculty (FEM), State University of Campinas (UNICAMP), 13083-970, Brazil; Post-Graduation Program of Biomaterials and Regenerative Medicine (PPGBMR), Surgery Department, (PUC-SP), 18030-070, Brazil.
Wound healing is a complex process involving a sequence of factors that can be disrupted, negatively impacting the quality of life for patients and overburdening healthcare systems. Advanced dressings obtained by electrospinning are highlighted by the optimization of this process, allowing air exchange and protection against microorganisms. Aiming to develop bioactive dressings, this study investigated the physicochemical, mechanical, microbiological, and in vitro biological properties of membranes containing 25 %, 50 %, 75 %, and 90 % copaiba oil (CO) co-electrospun with poly(L-co-D,L-lactic acid) (PLDLA) and natural rubber latex (NR).
View Article and Find Full Text PDFThe importance of microbiology reference laboratories and adequate funding for infectious disease surveillance.
Lancet Digit Health
December 2024
Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:
Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health.
View Article and Find Full Text PDFEfficient Photolysis of Multidrug-Resistant Polymicrobial Biofilms.
Adv Sci (Weinh)
December 2024
Wellman Center for Photomedicine, Massachusetts General Hospital, Department of Dermatology, Harvard Medical School, 50 Blossom Street, Boston, MA, 02114, USA.
Chronic wounds are prone to infections with multidrug-resistant bacteria, forming polymicrobial biofilms that limit treatment options and increase the risk of severe complications. Current cleansing options are insufficient to disrupt and remove tenacious biofilms; antibiotic treatments, on the other hand, often fall short against these biofilm-embedded bacteria. This study explores an non-antibiotic approach that extends beyond conventional porphyrin-based phototherapy by using blue light (BL) in conjunction with ferric ions (Fe(III)) to disrupt and eradicate biofilms.
View Article and Find Full Text PDFBioactive electrospun polylactic acid/chlorogenic acid-modified chitosan bilayer sponge for acute infection wound healing and rapid coagulation.
Biomater Sci
December 2024
Medical Research center, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Acute severe trauma is often associated with rapid blood loss and a high risk of infection. Based on these concerns, this study successfully constructed a multifunctional dual-layer bioactive sponge PCCT with rapid hemostatic and infection-preventing ability. Its external surface is an electrospun poly(lactic acid) (PLA) nanofiber thin film layer, which ensures its high air permeability and effectively protects against external bacterial invasion.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!