Purpose: The parasympathetic effects of the sphenopalatine ganglion (SPG) on the cerebral vasculature provide a compelling rationale for its therapeutic application in cerebrovascular ischemia. In recent years, attempts have been made to stimulate the SPG to achieve beneficial effects on cerebral circulation.
Methods: This review synthesizes the available publications on SPG stimulation. It critically evaluates the evidence from preclinical studies and clinical trials to assess its potential as a treatment for acute cerebrovascular disorders and outlines aspects that still require more study.
Results: The medical literature provides consistent evidence of the significant effects of stimulating the SPG on cerebrovascular circulation. In addition, considerable evidence supports the therapeutic role of SPG stimulation in patients with cerebral ischemia.
Conclusion: Given the current understanding, future research could explore the potential of SPG stimulation as a non-reperfusion intervention to improve long-term outcomes for individuals with ischemic cerebrovascular conditions.
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http://dx.doi.org/10.1007/s10286-024-01085-6 | DOI Listing |
Clin Auton Res
December 2024
Facultad de Medicina, Universidad Autónoma de Sinaloa, C. Sauces, s/n, 80019, Culiacán, SIN, Mexico.
Purpose: The parasympathetic effects of the sphenopalatine ganglion (SPG) on the cerebral vasculature provide a compelling rationale for its therapeutic application in cerebrovascular ischemia. In recent years, attempts have been made to stimulate the SPG to achieve beneficial effects on cerebral circulation.
Methods: This review synthesizes the available publications on SPG stimulation.
Acta Biomater
January 2025
School of Chemistry and Life Science, Changchun University of Technology, Changchun 130012, China. Electronic address:
Mol Nutr Food Res
November 2024
School of life Sciences, Anhui University Hefei, Hefei, 230601, P. R. China.
Scope: Cordyceps cicadae polysaccharides have received attention due to their potential in treating hyperglycemia and enhancing renal function. The beneficial effect of the purified C. cicadae polysaccharides fraction (CCP-1) on the reproductive impairments and spermatogenesis dysfunction of immunocompromised mice is unavailable and is studied herein.
View Article and Find Full Text PDFThe January 2022 eruption of the Hunga Tonga-Hunga Ha'apai (HTHH) volcano discharged 2,900 teragrams of ejecta, most of which was deposited in the South Pacific Ocean. Here we investigate its impact on the biogeochemistry of the South Pacific Gyre (SPG) using samples collected during the GEOTRACES cruise GP21 in February-April 2022. Surface water neodymium isotopes and rare earth element compositions showed a marked volcanic impact in the western SPG, potentially extending to the eastern region.
View Article and Find Full Text PDFElife
April 2024
Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.
Obstructive sleep apnea (OSA) is a prevalent sleep-related breathing disorder that results in multiple bouts of intermittent hypoxia. OSA has many neurological and systemic comorbidities, including dysphagia, or disordered swallow, and discoordination with breathing. However, the mechanism in which chronic intermittent hypoxia (CIH) causes dysphagia is unknown.
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