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[TREATMENT UPDATES IN OCULAR ONCOLOGY]. | LitMetric

[TREATMENT UPDATES IN OCULAR ONCOLOGY].

Harefuah

Ophthalmology Department, Shaare Tzedek Medical Center.

Published: December 2024

AI Article Synopsis

  • Malignant tumors of the eye, while rare, significantly impact patients' lives and vision, with retinoblastoma in children and uveal melanoma in adults being the most common types.
  • Managing these tumors poses challenges, such as controlling intraocular spread which affects survival rates, and dealing with eyelid tumors that might invade ocular tissue, complicating surgical removal.
  • Recent advancements in treatment over the past decade aim to enhance patient survival and preserve vision, including emerging therapies for both common tumors and rare types like conjunctival melanoma.

Article Abstract

Malignant tumors of the eye are uncommon, yet of great importance due to their effect on the patient's life and vision. The most common primary intraocular tumors are retinoblastoma in children and uveal melanoma in adults. The most common periocular tumor is basal cell carcinoma in eyelids. Management of these tumors can be challenging. On one hand, it can be difficult to control intraocular tumors like retinoblastoma or uveal melanoma from spreading out of the eye which will decrease the chances of survival of these patients. On the other hand, in eyelid tumors that have spread into the ocular tissue, this can make it surgically non-removable. In the past decades, many new treatments, local and systemic, have emerged with the main aim of saving the patient's life, as well as saving the globe of the eye and when possible, the vision. This has improved the overall survival of these patients. In this article, we reviewed the latest advances in the treatment of these tumors in the past decade. In addition, we reviewed the advances in the management and treatment of conjunctival melanoma, a very rare but lethal malignant tumor of the eye.

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