Beyond the pelvis: A case of umbilical endometriosis.

Radiol Case Rep

Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.

Published: February 2025

AI Article Synopsis

  • Umbilical endometriosis is a rare condition where functional endometrial tissue grows at the umbilicus, accounting for 0.5% to 1% of extragenital endometriosis cases, and its causes are not well understood.
  • A 34-year-old woman with no major surgical history experienced cyclic pain around her umbilicus, leading to further examination.
  • Physical and MRI exams revealed a nodule at the umbilicus, which was surgically removed, and histological analysis confirmed the diagnosis of endometriosis.

Article Abstract

Umbilical endometriosis is defined as an ectopic localization of functional endometrium at the level of the umbilicus. It is a rare condition, representing 0.5% to 1% of all extragenital endometriosis cases, and its pathophysiology is poorly understood. We report the case of a 34-year-old woman, G2P2, with no significant surgical history, admitted for cyclic umbilical pain. Physical examination revealed a grayish nodule at the umbilicus and MRI showed a parietal umbilical nodule suggestive of an endometrioma. The patient underwent resection of the umbilical nodule and the definitive histological study confirmed endometriosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650143PMC
http://dx.doi.org/10.1016/j.radcr.2024.10.146DOI Listing

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Article Synopsis
  • Umbilical endometriosis is a rare condition where functional endometrial tissue grows at the umbilicus, accounting for 0.5% to 1% of extragenital endometriosis cases, and its causes are not well understood.
  • A 34-year-old woman with no major surgical history experienced cyclic pain around her umbilicus, leading to further examination.
  • Physical and MRI exams revealed a nodule at the umbilicus, which was surgically removed, and histological analysis confirmed the diagnosis of endometriosis.
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Primary Umbilical Endometriosis (Villar's Nodule): A Case Report.

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December 2024

Gynecology and Obstetric Department, Kabul University of Medical Science, Shahr Ara University Hospital, Kabul, Afghanistan.

Primary umbilical endometriosis is a rare condition in which there is endometrial glands and stroma in the umbilicus. Primary umbilical endometriosis is also called villar's nodule. This condition is a diagnostic challenge, the pathophysiology of the disease is not well defined and should be considered in all other pathologies of the umbilicus.

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Article Synopsis
  • Umbilical endometriosis, also known as Villar's nodule, occurs when endometrial tissue is found in the umbilicus, affecting 0.5%-1% of endometriosis cases, and can be categorized as primary or secondary based on a patient's surgical history.
  • A significant case is presented involving a 30-year-old woman who had symptoms consistent with primary umbilical endometriosis for five years, which was confirmed through histological examination and found to coexist with a uterine fibroid.
  • For women of reproductive age presenting umbilical pain and nodules linked to their menstrual cycle, primary umbilical endometriosis should be considered, with surgery being the preferred treatment that can vary depending on the
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Endometriosis is a multifactorial gynecological disease, with angiogenesis as a key hallmark. The role of exosomal microRNAs (miRNAs) in endometriosis is not well understood. This study investigates differentially expressed exosomal miRNAs linked to angiogenesis in endometriosis, clarifies their molecular mechanisms, and identifies potential targets.

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