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Amyotrophic lateral sclerosis in a tricenarian female. | LitMetric

Amyotrophic lateral sclerosis in a tricenarian female.

Radiol Case Rep

Deptartment of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India 442001.

Published: February 2025

AI Article Synopsis

  • ALS is a motor neuron disease that causes the gradual degeneration of both upper and lower motor neurons, typically affecting individuals over 60 years old.
  • A rare case of ALS is presented involving a 31-year-old woman who experienced progressive limb weakness and muscle wasting.
  • The study highlights notable MRI findings, specifically the "wine glass sign," in the context of this unusual early-onset ALS case.

Article Abstract

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by the progressive degeneration of the upper and lower motor neurons. This disease is mostly observed in patients of the 6th decade or above, and it is extremely rare to observe this pathology in patients less than 50 years of age. This manuscript depicts the magnetic resonance imaging findings of ALS showing a wine glass sign in a 31-year-old female from a rural area with complaints of progressive limb weakness and muscle wasting.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650128PMC
http://dx.doi.org/10.1016/j.radcr.2024.10.153DOI Listing

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