[Progress in the diagnosis and treatment of acute pancreatitis complicated by biliary tract diseases].

Zhonghua Wai Ke Za Zhi

Department of Pancreatic and Biliary Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin150001, China.

Published: December 2024

AI Article Synopsis

  • Acute pancreatitis is a surgical emergency that can lead to serious local complications, particularly affecting the biliary system, including acute acalculous cholecystitis (AAC) and biliary stricture.
  • AAC generally arises in the later stages of acute pancreatitis and can worsen inflammation, potentially causing organ failure.
  • The article reviews recent research to clarify the causes, diagnostic challenges, and treatment options for biliary complications that can occur due to acute pancreatitis, emphasizing the lack of clear treatment guidelines.

Article Abstract

Acute pancreatitis is a common surgical emergency characterized by severe local or systemic complications during its progression. Diseases of the biliary system are among the serious local complications of acute pancreatitis, primarily including acute acalculous cholecystitis (AAC) and biliary stricture. AAC often occurs in the later stages of acute pancreatitis, exacerbating systemic inflammation and leading to organ failure and life-threatening conditions in severe cases. Biliary stricture is a rare but serious long-term complication of acute pancreatitis, which can induce cholangitis, progressive liver function impairment, and secondary biliary cirrhosis. Due to the clinical symptoms of acute pancreatitis that can mask biliary system diseases, some patients may not receive timely diagnosis and treatment for concurrent biliary issues during the onset of acute pancreatitis, which can be life-threatening in severe cases. Currently, the ideal treatment strategy for biliary system complications secondary to acute pancreatitis remains unclear, lacking definitive guidelines or consensus. This article integrates recent research developments from both domestic and international studies to elucidate the pathogenesis, diagnosis, and treatment strategies for biliary system complications secondary to acute pancreatitis.

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http://dx.doi.org/10.3760/cma.j.cn112139-20240708-00330DOI Listing

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