[Evaluation of the effectiveness of the drug Cortexin in combination with the use of the application Aphasia.No (Afaziyam.Net) in the correction of speech disorders in patients with cerebral infarction].

Objective: Assessing the effectiveness of using a complex that includes the use of the drug Cortexin and classes using the mobile application Aphasia.No (Afaziyam.Net) in working with speech disorders in patients with acute stroke.

Material And Methods: The study involved 71 patients aged from 40 to 85 years with diagnoses of the ONCM group (I63-I64), as well as complications aphasia, 50 of them consented to neuropsychological rehabilitation using the application Aphasia.No (Afaziyam.Net) and received the drug Cortexin as a peptide drug at a dose of 10 mg 2 times a day intramuscularly (IG). 21 patients made up the comparison group. To assess the effectiveness of the rehabilitation complex, the following psychodiagnostic methods were used: MoCA, MMSE, a set of tasks for the study of speech, writing, reading, and the HADS scale.

Results: The average score based on the results of a comprehensive study of speech, writing and reading in the group on day 2 in the hospital was: speech - 141.8±21.6 (normal - 262 points); writing - 20.5±4.23 (normal - 44 points); reading - 14.5±1.87 (normal - 29 points) points. An examination before discharge in IG showed the following results: speech - 214.3±15.9; writing - 31.5±4.5; reading - 24.4±4.7 points. The differences compared to the baseline and the 2 group were statistically significant.

Conclusion: The complex treatment used in the work can be recommended as an effective tool in working with speech disorders in patients with acute stroke. In addition, the program has a positive effect on the psycho-emotional state.